Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed with results

Key Signals

3 with results75% success

Data Visualizations

Phase Distribution

13Total
Not Applicable (3)
P 1 (2)
P 2 (8)

Trial Status

Recruiting8
Completed6
Unknown2
Active Not Recruiting2
Terminated2
Withdrawn1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT04564989Recruiting

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

NCT04858269Phase 2Recruiting

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

NCT07063212Phase 2Recruiting

A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

NCT03829722Phase 2CompletedPrimary

Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer

NCT07337122Completed

Collagen Matrix in Oral Cancer Surgery

NCT04124198Not ApplicableActive Not Recruiting

Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

NCT04445064Phase 2TerminatedPrimary

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

NCT03381183Phase 1Completed

IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma

NCT04916002Phase 2Terminated

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

NCT04725396Not ApplicableCompletedPrimary

Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC

NCT06088381Phase 2Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

NCT05582122Phase 2RecruitingPrimary

SURVEILLE-HPV: Evaluation of HPV16 Circulating DNA as Biomarker to Detect the Recurrence, in Order to Improve Post Therapeutic Surveillance of HPV16-driven Oropharyngeal Cancers

NCT05278039Not ApplicableRecruiting

Training Swallowing Initiation During Expiration

NCT05451303Recruiting

Detection of Oral and Throat Cancers Using OralViome Cancer Testing System

NCT03715946Phase 2Completed

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

NCT04892875Phase 1Withdrawn

A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers

NCT05904327Active Not RecruitingPrimary

Circulating Biomarkers in Oropharyngeal Cancers

NCT05649865RecruitingPrimary

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

NCT04359199Unknown

QUantitative Assessment of Swallowing After Radiation (QUASAR)

NCT03148665Completed

Saliva-based Detection of CD44

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