Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

16.7%

4 terminated out of 24 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

8%

2 trials in Phase 3/4

Results Transparency

70%

7 of 10 completed with results

Key Signals

7 with results71% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (6)
P 1 (1)
P 2 (9)
P 3 (2)

Trial Status

Completed10
Terminated4
Unknown4
Withdrawn2
Active Not Recruiting2
Recruiting1

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT04266093Enrolling By Invitation

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

NCT06167291Phase 2Active Not RecruitingPrimary

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

NCT04124198Not ApplicableActive Not Recruiting

Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

NCT02792322Not ApplicableCompletedPrimary

Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and Neck

NCT02281955Phase 2Completed

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

NCT06642324Recruiting

Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas

NCT01530997Phase 2Completed

De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca

NCT03077243Phase 2Completed

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

NCT05412628Not ApplicableUnknown

Investigating the Association Between Microbiota and Esophageal/Oropharyngeal Cancer

NCT04015336Phase 2Terminated

E7 TCR Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal Cancer

NCT03239834Completed

Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making

NCT01687413Phase 3TerminatedPrimary

Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer

NCT04044950Phase 2Withdrawn

A Phase II Study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer

NCT00721799Phase 2Completed

F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients

NCT03010813Not ApplicableCompleted

A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery

NCT03074110Not ApplicableCompletedPrimary

Isocapnic Hyperventilation - an Alternative Method

NCT01525927Phase 2TerminatedPrimary

Study of Chemotherapy Prior to Radiotherapy and Chemotherapy in Patients With HPV Associated Cancer of the Oral Cavity

NCT02298595Phase 1Withdrawn

Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

NCT02045186Not ApplicableTerminated

Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)

NCT00918710UnknownPrimary

Human Papillomavirus and Oropharynx Carcinoma

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