Key Insights

Highlights

Success Rate

89% trial completion (above average)

Published Results

20 trials with published results (21%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

5.2%

5 terminated out of 96 trials

Success Rate

89.4%

+2.8% vs benchmark

Late-Stage Pipeline

7%

7 trials in Phase 3/4

Results Transparency

48%

20 of 42 completed with results

Key Signals

20 with results89% success

Data Visualizations

Phase Distribution

73Total
Not Applicable (25)
P 1 (14)
P 2 (27)
P 3 (6)
P 4 (1)

Trial Status

Completed42
Recruiting15
Active Not Recruiting11
Unknown11
Withdrawn8
Terminated5

Trial Success Rate

89.4%

Benchmark: 86.6%

Based on 42 completed trials

Clinical Trials (96)

Showing 20 of 20 trials
NCT03644563Active Not RecruitingPrimary

Men and Women Offering Understanding of Throat HPV

NCT06305676RecruitingPrimary

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

NCT05814549Active Not RecruitingPrimary

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

NCT04708470Phase 1CompletedPrimary

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

NCT07832266Phase 1Not Yet Recruiting

Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT)

NCT00498875Active Not RecruitingPrimary

Depression and Adherence in Head and Neck Cancer

NCT04432597Phase 1Completed

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

NCT07418034Phase 2Not Yet Recruiting

A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)

NCT06445114Phase 2RecruitingPrimary

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

NCT03729518Not ApplicableCompletedPrimary

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

NCT05451004Phase 3RecruitingPrimary

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

NCT04287868Phase 1Completed

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT03224000Phase 2Active Not Recruiting

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

NCT06747390Phase 1Recruiting

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

NCT05363709Phase 2Withdrawn

BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients

NCT04116047Phase 3Active Not RecruitingPrimary

CompARE: Escalating Treatment of Intermediate and High-risk Oropharyngeal Cancer (OPC)

NCT07209189Phase 2Recruiting

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

NCT05491512Phase 2Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

NCT04251949Phase 2Completed

Evaluation of the Photobiomodulation Using LED Lamp for Curative Treatment of Radio-induced Mucositis.

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