Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

14.3%

2 terminated out of 14 trials

Success Rate

84.6%

-1.9% vs benchmark

Late-Stage Pipeline

29%

4 trials in Phase 3/4

Results Transparency

36%

4 of 11 completed with results

Key Signals

4 with results85% success

Data Visualizations

Phase Distribution

9Total
P 1 (1)
P 2 (4)
P 3 (1)
P 4 (3)

Trial Status

Completed11
Terminated2
Unknown1

Trial Success Rate

84.6%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT02813148CompletedPrimary

Naloxegol Drug Utilization Post Authorisation Safety Study

NCT02813369TerminatedPrimary

Naloxegol Health Outcome Post Authorisation Safety Study

NCT03638440CompletedPrimary

Real World Observational Study of Naloxegol for Patients With Cancer Pain Diagnosed With OIC.

NCT02813356UnknownPrimary

Naloxegol US PMR CV Safety.

NCT01117051Phase 3Terminated

Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation

NCT01401985Phase 2CompletedPrimary

A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)

NCT01459926Phase 2CompletedPrimary

A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation

NCT01109511Phase 4Completed

A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy

NCT01207427Phase 2CompletedPrimary

Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain

NCT03060512Phase 4CompletedPrimary

To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation

NCT01957046Phase 4CompletedPrimary

A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC).

NCT01812733Completed

Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives

NCT01623609Phase 1CompletedPrimary

Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol

NCT00984334Phase 2Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Showing all 14 trials

Research Network

Activity Timeline