Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

50 trials with published results (30%)

Research Maturity

130 completed trials (77% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

7.1%

12 terminated out of 169 trials

Success Rate

91.5%

+5.0% vs benchmark

Late-Stage Pipeline

56%

94 trials in Phase 3/4

Results Transparency

38%

50 of 130 completed with results

Key Signals

50 with results92% success12 terminated

Data Visualizations

Phase Distribution

153Total
Not Applicable (16)
P 1 (11)
P 2 (32)
P 3 (51)
P 4 (43)

Trial Status

Completed130
Terminated12
Unknown9
Recruiting7
Active Not Recruiting5
Withdrawn5

Trial Success Rate

91.5%

Benchmark: 86.5%

Based on 130 completed trials

Clinical Trials (169)

Showing 20 of 20 trials
NCT05821855Phase 4Active Not RecruitingPrimary

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China

NCT07520175Enrolling By InvitationPrimary

A Study of Outcomes Following Bio-Reinforced Canaloplasty in Eyes With Open-Angle Glaucoma

NCT04499248Phase 1RecruitingPrimary

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

NCT07303257Recruiting

Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options

NCT07217678Phase 4Recruiting

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

NCT05411198Phase 3CompletedPrimary

Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma

NCT03267134Not ApplicableCompletedPrimary

Hydrus Microstent for Refractory Open-Angle Glaucoma

NCT02928289Not ApplicableTerminatedPrimary

Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle Glaucoma

NCT03891446Phase 3Active Not RecruitingPrimary

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

NCT03850782Phase 3CompletedPrimary

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

NCT04647214CompletedPrimary

18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)

NCT07081347Not ApplicableActive Not Recruiting

This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety of the MINT® Procedure in Open Angle Glaucoma Eyes.

NCT06953349RecruitingPrimary

Efficacy of Surgical Systems in Combination With Phacoemulsification: a Retrospective Analysis

NCT06885827Not ApplicableRecruitingPrimary

Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients

NCT05822245Phase 1Active Not RecruitingPrimary

A Study of PER-001 in Participants With Open-Angle Glaucoma

NCT05338606UnknownPrimary

Expanded Access to Bimatoprost (Durysta)

NCT06792422Phase 4Recruiting

A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma

NCT06741774Not ApplicableActive Not RecruitingPrimary

Efficacy and Safety of Trabecular Meshwork Microstent Drainage System ( MicroCOGO )

NCT06267274Phase 1RecruitingPrimary

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

NCT00804323Not ApplicableTerminatedPrimary

PASCAL Trabeculoplasty

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