Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

7.1%

2 terminated out of 28 trials

Success Rate

88.2%

+1.7% vs benchmark

Late-Stage Pipeline

25%

7 trials in Phase 3/4

Results Transparency

27%

4 of 15 completed with results

Key Signals

4 with results88% success

Data Visualizations

Phase Distribution

22Total
Not Applicable (6)
P 1 (2)
P 2 (7)
P 3 (5)
P 4 (2)

Trial Status

Completed15
Recruiting3
Active Not Recruiting3
Terminated2
Withdrawn2
Not Yet Recruiting2

Trial Success Rate

88.2%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT00001230Recruiting

Host Response to Infection and Treatment in Filarial Diseases

NCT07506967Not ApplicableNot Yet Recruiting

Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers

NCT04311671Phase 3CompletedPrimary

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

NCT03876262Phase 3Active Not RecruitingPrimary

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

NCT06070116Phase 2Active Not Recruiting

Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis

NCT07248462Not ApplicableNot Yet Recruiting

Integrating Mental Health Into Neglected Tropical Disease Care in Ghana

NCT07145736Phase 4RecruitingPrimary

Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases

NCT03962062Phase 1CompletedPrimary

A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years

NCT04035174Not ApplicableWithdrawnPrimary

Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa

NCT06350851Not ApplicableRecruitingPrimary

Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination

NCT04913610Phase 2TerminatedPrimary

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection

NCT00127504Phase 2CompletedPrimary

Clinical Trial of Rifampin and Azithromycin for the Treatment of River Blindness

NCT04188301Phase 2CompletedPrimary

Safety and Efficacy of IDA for Onchocerciasis

NCT05180461Phase 2Active Not RecruitingPrimary

Emodepside Phase II Trial for Treatment of Onchocerciasis

NCT05750043CompletedPrimary

Effect of Onchocerciasis Elimination Measures on the Incidence of Epilepsy in Maridi, South Sudan

NCT05749653Not ApplicableCompletedPrimary

Impact of a Bi-annual CDTI on the Incidence of Epilepsy in an Onchocerciasis-endemic Area

NCT05084560Phase 1Terminated

Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug

NCT00300768Phase 2CompletedPrimary

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

NCT01905436Completed

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia

NCT03517462Not ApplicableCompletedPrimary

Ocular Changes After Ivermectin - (DOLF IVM/Oncho)

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