Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 54/100

Termination Rate

27.3%

3 terminated out of 11 trials

Success Rate

72.7%

-13.8% vs benchmark

Late-Stage Pipeline

27%

3 trials in Phase 3/4

Results Transparency

50%

4 of 8 completed with results

Key Signals

4 with results73% success

Data Visualizations

Phase Distribution

11Total
P 1 (7)
P 2 (1)
P 3 (3)

Trial Status

Completed8
Terminated3

Trial Success Rate

72.7%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (11)

Showing 11 of 11 trials
NCT02292771Phase 3TerminatedPrimary

A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour

NCT02377466Phase 3TerminatedPrimary

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor

NCT02292784Phase 3CompletedPrimary

Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies

NCT00404768Phase 2CompletedPrimary

The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor

NCT01627587Phase 1CompletedPrimary

A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole

NCT01702376Phase 1CompletedPrimary

This Study Will Investigate the Effect of Single Oral Doses of Retosiban on Cardiac Repolarization, With Moxifloxacin as a Positive Control in Healthy Volunteers.

NCT01867996Phase 1CompletedPrimary

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Retosiban (GSK221149) When Dosed With Efavirenz (EFZ)

NCT02377414Phase 1CompletedPrimary

Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women

NCT00449709Phase 1TerminatedPrimary

A Study To Assess The Pharmacokinetics Of Different Modified Release Formulations Of GSK221149 In Healthy Adult Subjects

NCT00457925Phase 1CompletedPrimary

Absorption, Distribution, Metabolism And Excretion Study For GSK221149A

NCT00549211Phase 1CompletedPrimary

A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.

Showing all 11 trials

Research Network

Activity Timeline