Key Insights

Highlights

Success Rate

69% trial completion

Published Results

12 trials with published results (19%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

20.6%

13 terminated out of 63 trials

Success Rate

69.0%

-17.5% vs benchmark

Late-Stage Pipeline

13%

8 trials in Phase 3/4

Results Transparency

41%

12 of 29 completed with results

Key Signals

12 with results69% success13 terminated

Data Visualizations

Phase Distribution

56Total
Not Applicable (9)
P 1 (26)
P 2 (13)
P 3 (7)
P 4 (1)

Trial Status

Completed29
Terminated13
Recruiting6
Active Not Recruiting5
Unknown5
Withdrawn2

Trial Success Rate

69.0%

Benchmark: 86.5%

Based on 29 completed trials

Clinical Trials (63)

Showing 20 of 20 trials
NCT06694454Phase 1Recruiting

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

NCT05642195Phase 1Suspended

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

NCT07144280Phase 3Recruiting

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

NCT03731585Not ApplicableActive Not RecruitingPrimary

Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment

NCT05358249Phase 1Active Not Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

NCT07284186Phase 1Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

NCT03678350Phase 1Completed

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

NCT02818920Phase 2CompletedPrimary

Neoadjuvant Pembrolizumab

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT06282991CompletedPrimary

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled

NCT01279408CompletedPrimary

Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC)

NCT06560645Phase 1Terminated

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT02432963Phase 1Active Not Recruiting

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

NCT00213798Not ApplicableCompletedPrimary

Detection of Plasma DNA in Non Small Cell and Small Cell Lung Cancer Patients

NCT05110196Phase 4CompletedPrimary

Study of Capmatinib in Indian Patients With MET Exon 14 Skipping Mutation Positive Advanced NSCLC.

NCT04042701Phase 1Active Not Recruiting

DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer

NCT02186847Phase 2Completed

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

NCT05393466Phase 1Not Yet RecruitingPrimary

BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT04000529Phase 1TerminatedPrimary

Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies

NCT06270082Phase 1Terminated

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

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