Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

18.8%

3 terminated out of 16 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

56%

5 of 9 completed with results

Key Signals

5 with results75% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (1)
Early P 1 (2)
P 1 (2)
P 2 (9)

Trial Status

Completed9
Terminated3
Active Not Recruiting2
Recruiting1
Unknown1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT04374305Phase 2RecruitingPrimary

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

NCT01552434Phase 1Active Not Recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

NCT05521048Phase 1Active Not RecruitingPrimary

Doxycycline in Cutaneous Schwannoma (NF2)

NCT02282917Early Phase 1Terminated

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

NCT05130866Phase 2TerminatedPrimary

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas

NCT01345136Phase 2TerminatedPrimary

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

NCT02129647Phase 2CompletedPrimary

Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

NCT02934256Phase 2Completed

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

NCT01767792Phase 2CompletedPrimary

Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas

NCT01125046Phase 2Completed

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

NCT01880749Early Phase 1CompletedPrimary

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

NCT02246231Not ApplicableCompletedPrimary

Effect of Implant Position on Magnetic Resonance Image Distortion

NCT02589912UnknownPrimary

Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients

NCT01207687Phase 2Completed

Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)

NCT03210285CompletedPrimary

WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data

NCT02104323Phase 2Completed

Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Showing all 16 trials

Research Network

Activity Timeline