Key Insights

Highlights

Success Rate

82% trial completion

Published Results

71 trials with published results (15%)

Research Maturity

235 completed trials (49% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.6%

51 terminated out of 480 trials

Success Rate

82.2%

-4.3% vs benchmark

Late-Stage Pipeline

6%

31 trials in Phase 3/4

Results Transparency

30%

71 of 235 completed with results

Key Signals

71 with results82% success51 terminated

Data Visualizations

Phase Distribution

405Total
Not Applicable (42)
Early P 1 (12)
P 1 (189)
P 2 (131)
P 3 (28)
P 4 (3)

Trial Status

Completed235
Recruiting77
Unknown55
Terminated51
Active Not Recruiting30
Withdrawn20

Trial Success Rate

82.2%

Benchmark: 86.5%

Based on 235 completed trials

Clinical Trials (480)

Showing 20 of 20 trials
NCT01857934Phase 2CompletedPrimary

Therapy for Children With Advanced Stage Neuroblastoma

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT04308330Phase 1Recruiting

Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

NCT06638931Phase 2Recruiting

Agnostic Therapy in Rare Solid Tumors

NCT06995872Phase 1RecruitingPrimary

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

NCT00295919Phase 1CompletedPrimary

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

NCT00646230Phase 1CompletedPrimary

N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma

NCT06172296Phase 3Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT00093353Phase 1Completed

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

NCT01109394Recruiting

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

NCT00083135Phase 1CompletedPrimary

N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantation

NCT01875601Phase 1Completed

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

NCT01005654Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

NCT00509353Phase 1CompletedPrimary

N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma

NCT01163383UnknownPrimary

131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access Protocol

NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT06541262Phase 1RecruitingPrimary

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT07516678RecruitingPrimary

Serial ctDNA and Molecular Residual Disease Monitoring in Neuroblastoma

NCT07518654Phase 1Not Yet Recruiting

Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma

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