Key Insights

Highlights

Success Rate

82% trial completion

Published Results

71 trials with published results (15%)

Research Maturity

236 completed trials (49% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.6%

51 terminated out of 483 trials

Success Rate

82.2%

-4.3% vs benchmark

Late-Stage Pipeline

6%

31 trials in Phase 3/4

Results Transparency

30%

71 of 236 completed with results

Key Signals

71 with results82% success51 terminated

Data Visualizations

Phase Distribution

408Total
Not Applicable (43)
Early P 1 (12)
P 1 (190)
P 2 (132)
P 3 (28)
P 4 (3)

Trial Status

Completed236
Recruiting74
Unknown54
Terminated51
Active Not Recruiting35
Withdrawn20

Trial Success Rate

82.2%

Benchmark: 86.5%

Based on 236 completed trials

Clinical Trials (483)

Showing 20 of 20 trials
NCT01875601Phase 1Completed

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

NCT03363373Phase 2Active Not RecruitingPrimary

Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow

NCT06172296Phase 3Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT04337177Phase 1Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT01109394Recruiting

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

NCT01005654Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

NCT06057948Phase 2RecruitingPrimary

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT01370330UnknownPrimary

131I-Labeled MIBG for Refractory Neuroblastoma: A Compassionate Use Protocol

NCT06528496Phase 2Recruiting

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

NCT06995872Phase 1RecruitingPrimary

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

NCT06450041Phase 2RecruitingPrimary

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

NCT07027748Phase 1RecruitingPrimary

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

NCT06942039Early Phase 1Recruiting

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

NCT04301843Phase 2Active Not RecruitingPrimary

Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

NCT04724369Phase 3Active Not RecruitingPrimary

Open-Label Study of 18F-mFBG for Imaging Neuroblastoma

NCT06541262Phase 1RecruitingPrimary

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT05489887Phase 2RecruitingPrimary

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

NCT04837547Phase 1RecruitingPrimary

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

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