Key Insights

Highlights

Success Rate

83% trial completion

Published Results

71 trials with published results (15%)

Research Maturity

241 completed trials (50% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.5%

51 terminated out of 484 trials

Success Rate

82.5%

-4.1% vs benchmark

Late-Stage Pipeline

6%

31 trials in Phase 3/4

Results Transparency

29%

71 of 241 completed with results

Key Signals

71 with results83% success51 terminated

Data Visualizations

Phase Distribution

408Total
Not Applicable (43)
Early P 1 (12)
P 1 (189)
P 2 (133)
P 3 (28)
P 4 (3)

Trial Status

Completed241
Recruiting71
Unknown54
Terminated51
Active Not Recruiting35
Withdrawn20

Trial Success Rate

82.5%

Benchmark: 86.6%

Based on 241 completed trials

Clinical Trials (484)

Showing 20 of 20 trials
NCT06172296Phase 3Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT01192555Phase 1Active Not RecruitingPrimary

Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastoma

NCT01109394Recruiting

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

NCT06000787Not ApplicableRecruiting

MCT for the Harvard/UCSF ROBIN Center

NCT03478462Phase 1Active Not Recruiting

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

NCT03373097Phase 1Active Not RecruitingPrimary

Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors

NCT04936529Phase 2RecruitingPrimary

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

NCT04724369Phase 3CompletedPrimary

Open-Label Study of 18F-mFBG for Imaging Neuroblastoma

NCT06995872Phase 1RecruitingPrimary

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

NCT04837547Phase 1Active Not RecruitingPrimary

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

NCT07833631CompletedPrimary

A Prospective Image Reevaluation Study to Assess the Efficacy of 18F-mFBG PET Imaging in Subjects With Neuroblastoma

NCT01005654Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

NCT01857934Phase 2CompletedPrimary

Therapy for Children With Advanced Stage Neuroblastoma

NCT05421897Phase 2Active Not RecruitingPrimary

Rapid Administration Pilot for Infusing Dinutuximab

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT06674811Recruiting

Biomarkers of Resiliency In Childhood Cancer Surgery

NCT05027386Phase 1CompletedPrimary

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II,Multi-center, Clinical Study.

NCT02559778Phase 2RecruitingPrimary

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

NCT06540963Phase 2RecruitingPrimary

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

NCT07358260Phase 1Recruiting

B7-H3.CD28Z.CART in Solid Tumors

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