Key Insights

Highlights

Success Rate

62% trial completion

Published Results

29 trials with published results (30%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

27.1%

26 terminated out of 96 trials

Success Rate

62.3%

-24.2% vs benchmark

Late-Stage Pipeline

5%

5 trials in Phase 3/4

Results Transparency

67%

29 of 43 completed with results

Key Signals

29 with results62% success26 terminated

Data Visualizations

Phase Distribution

88Total
Not Applicable (3)
P 1 (39)
P 2 (41)
P 3 (4)
P 4 (1)

Trial Status

Completed43
Terminated26
Unknown8
Recruiting7
Active Not Recruiting5
Withdrawn4

Trial Success Rate

62.3%

Benchmark: 86.5%

Based on 43 completed trials

Clinical Trials (96)

Showing 20 of 20 trials
NCT04401748Phase 3Active Not RecruitingPrimary

Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

NCT04639024Phase 2Terminated

ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN

NCT00923442Enrolling By Invitation

Biology Studies of Hematologic Cancers

NCT02944955Phase 2Not Yet RecruitingPrimary

A Study of BLEX 404 Oral Liquid in Patients With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-Risk Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML)

NCT03173937Phase 1Recruiting

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

NCT01758042Not ApplicableCompleted

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

NCT02730299Phase 3Completed

Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS

NCT05665530Phase 1Completed

A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

NCT05143996Phase 1Recruiting

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

NCT03613532Phase 1Active Not Recruiting

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

NCT06294275Phase 1CompletedPrimary

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

NCT07008820RecruitingPrimary

Patient Reported Outcomes and Patient Voice Among Patients Diagnosed With Low Risk Myelodysplastic Syndrome (LR-MDS) or Unexplained Anemia In Japan

NCT04608110Phase 1RecruitingPrimary

A Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome

NCT05534620Phase 1Recruiting

Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics

NCT02143830Phase 2Recruiting

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

NCT04878432Phase 2TerminatedPrimary

STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

NCT04812548Phase 2TerminatedPrimary

A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants

NCT02158858Phase 1Completed

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

NCT02790515Phase 2Active Not Recruiting

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

NCT02793544Phase 2CompletedPrimary

HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide

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