Key Insights

Highlights

Success Rate

83% trial completion

Published Results

17 trials with published results (12%)

Research Maturity

59 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.2%

12 terminated out of 147 trials

Success Rate

83.1%

-3.4% vs benchmark

Late-Stage Pipeline

6%

9 trials in Phase 3/4

Results Transparency

29%

17 of 59 completed with results

Key Signals

17 with results83% success12 terminated

Data Visualizations

Phase Distribution

94Total
Not Applicable (36)
Early P 1 (5)
P 1 (17)
P 2 (27)
P 3 (7)
P 4 (2)

Trial Status

Completed59
Recruiting39
Unknown15
Active Not Recruiting13
Terminated12
Not Yet Recruiting4

Trial Success Rate

83.1%

Benchmark: 86.5%

Based on 59 completed trials

Clinical Trials (147)

Showing 20 of 20 trials
NCT07531433UnknownPrimary

Post-Trial Access to ATH434 for Patients With Multiple System Atrophy

NCT05104476Phase 2Active Not RecruitingPrimary

A Study of Lu AF82422 in Participants With Multiple System Atrophy

NCT07518810Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Butylphthalide in the Treatment of Multiple System Atrophy

NCT07197866Phase 2RecruitingPrimary

An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

NCT02071459Phase 2CompletedPrimary

Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA

NCT06683365Phase 1RecruitingPrimary

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

NCT03648905Active Not Recruiting

Clinical Laboratory Evaluation of Chronic Autonomic Failure

NCT07476352Early Phase 1Not Yet RecruitingPrimary

Expansion Study of ALT001 in Patients With Multiple System Atrophy

NCT04246437Phase 1Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

NCT05634876Phase 1CompletedPrimary

UB-312 in Patients With Synucleinopathies

NCT02726711Phase 1Active Not RecruitingPrimary

Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic

NCT06671938Phase 2Active Not Recruiting

Safety, Tolerability, and Pharmacokinetics of Exidavnemab in Patients With Parkinson's Disease and Patients With Multiple System Atrophy

NCT07238062UnknownPrimary

"An Intermediate Size Patient Population Expanded Access Protocol to Evaluate the Safety and Efficacy of Allogeneic HB-adMSCs (Hope Biosciences - Adipose Derived Mesenchymal Stem Cells) for the Treatment of Multiple System Atrophy."

NCT05222386Not ApplicableActive Not Recruiting

Community Outreach for Palliative Engagement -- Parkinson Disease

NCT07353463Recruiting

Shanghai Clinical Cohort - Parkinson's Disease (Reserve)

NCT06738862Completed

[18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients

NCT06568237Phase 2RecruitingPrimary

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

NCT06706622Phase 3Active Not RecruitingPrimary

A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)

NCT05121012RecruitingPrimary

Synaptic Loss in Multiple System Atrophy

NCT07392411Recruiting

Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

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