Key Insights

Highlights

Success Rate

85% trial completion

Published Results

19 trials with published results (12%)

Research Maturity

68 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.7%

12 terminated out of 155 trials

Success Rate

85.0%

-1.6% vs benchmark

Late-Stage Pipeline

6%

9 trials in Phase 3/4

Results Transparency

28%

19 of 68 completed with results

Key Signals

19 with results85% success12 terminated

Data Visualizations

Phase Distribution

98Total
Not Applicable (38)
Early P 1 (5)
P 1 (18)
P 2 (28)
P 3 (7)
P 4 (2)

Trial Status

Completed68
Recruiting36
Unknown13
Terminated12
Active Not Recruiting12
Not Yet Recruiting7

Trial Success Rate

85.0%

Benchmark: 86.6%

Based on 68 completed trials

Clinical Trials (155)

Showing 20 of 20 trials
NCT07197866Phase 2RecruitingPrimary

An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

NCT03648905Completed

Clinical Laboratory Evaluation of Chronic Autonomic Failure

NCT05526391Phase 2CompletedPrimary

A Study of TAK-341 in Treatment of Multiple System Atrophy

NCT07729852Phase 2Not Yet RecruitingPrimary

Open-Label Access to ATH434 for Patients Who Completed Study ATH434-201 in France

NCT04472130Recruiting

Neurodegenerative Diseases Registry

NCT07827963Not Yet Recruiting

VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism

NCT01353183Not ApplicableCompleted

Analysis of the Enteric Nervous System Using Colonic Biopsies

NCT07476352Early Phase 1RecruitingPrimary

Expansion Study of ALT001 in Patients With Multiple System Atrophy

NCT07805967RecruitingPrimary

Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)

NCT06596746Recruiting

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

NCT06683365Phase 1RecruitingPrimary

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

NCT07657520WithdrawnPrimary

High-Altitude Neurodegeneration Cohort (HANC) Study

NCT06671938Phase 2Completed

Safety, Tolerability, and Pharmacokinetics of Exidavnemab in Patients With Parkinson's Disease and Patients With Multiple System Atrophy

NCT06848231Phase 2Active Not RecruitingPrimary

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

NCT07774585Phase 1Not Yet RecruitingPrimary

A Prospective Exploratory Study of the Safety and Preliminary Efficacy of the α-Syn H21 Monoclonal Antibody in Patients With Multiple System Atrophy

NCT06209515Active Not Recruiting

Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study

NCT04620382Early Phase 1Completed

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

NCT05699460Completed

Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy

NCT06568237Phase 2RecruitingPrimary

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

NCT06706622Phase 3Active Not RecruitingPrimary

A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)

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Research Network

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