Key Insights

Highlights

Success Rate

86% trial completion

Published Results

23 trials with published results (11%)

Research Maturity

66 completed trials (31% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.2%

11 terminated out of 213 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

4%

8 trials in Phase 3/4

Results Transparency

35%

23 of 66 completed with results

Key Signals

23 with results86% success11 terminated

Data Visualizations

Phase Distribution

122Total
Not Applicable (99)
Early P 1 (1)
P 1 (10)
P 2 (4)
P 3 (1)
P 4 (7)

Trial Status

Completed66
Recruiting50
Unknown46
Not Yet Recruiting19
Active Not Recruiting12
Terminated11

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 66 completed trials

Clinical Trials (213)

Showing 20 of 20 trials
NCT04729933Not ApplicableActive Not Recruiting

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

NCT06465745Not ApplicableRecruitingPrimary

ATLAS (AltaValve) Pivotal Trial

NCT06539416CompletedPrimary

Mixed Reality in MitraClip Implantation: Preliminary Case Series

NCT06661200Not ApplicableCompleted

Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique

NCT07450911Phase 1RecruitingPrimary

The REValve Clinical Trial an Evaluation Of the ReValve Palmetto Valve for the Replacement of the Native Mitral VaLVE

NCT03433274Not ApplicableActive Not RecruitingPrimary

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

NCT03230747Not ApplicableActive Not RecruitingPrimary

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation

NCT06600191Not ApplicableRecruitingPrimary

Capstan Medical TMVR Study: FIH

NCT05061004Not ApplicableRecruitingPrimary

Cephea Early Feasibility Study

NCT03706833Not ApplicableActive Not Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

NCT05496998Not ApplicableRecruitingPrimary

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

NCT06241430Not ApplicableRecruiting

The CardioClip Study

NCT07671820Not ApplicableNot Yet RecruitingPrimary

Anchord Mitral Chordal Repair System - FIH

NCT03813524Not ApplicableTerminatedPrimary

Cardiovalve Transfemoral Mitral Valve System

NCT07069673RecruitingPrimary

Abbott Cephea Mitral Valve Disease Registry

NCT07366723Not ApplicableActive Not Recruiting

The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation

NCT07632794Active Not RecruitingPrimary

Artificial Intelligence Assisting Transcatheter Mitral Edge-to-Edge Repair

NCT07623083Not Yet Recruiting

Evaluation of a Management Algorithm for TAVI Patients With Concomitant Mitral or Tricuspid Regurgitation

NCT07130994Not ApplicableNot Yet RecruitingPrimary

Reduction of Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

NCT07605624Not Yet Recruiting

Active Post-Market Surveillance of Innovative Devices for Valvular Heart Disease

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