Key Insights

Highlights

Success Rate

85% trial completion

Published Results

21 trials with published results (10%)

Research Maturity

64 completed trials (31% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.3%

11 terminated out of 208 trials

Success Rate

85.3%

-1.2% vs benchmark

Late-Stage Pipeline

4%

8 trials in Phase 3/4

Results Transparency

33%

21 of 64 completed with results

Key Signals

21 with results85% success11 terminated

Data Visualizations

Phase Distribution

120Total
Not Applicable (97)
Early P 1 (1)
P 1 (10)
P 2 (4)
P 3 (1)
P 4 (7)

Trial Status

Completed64
Recruiting51
Unknown46
Not Yet Recruiting16
Active Not Recruiting11
Terminated11

Trial Success Rate

85.3%

Benchmark: 86.5%

Based on 64 completed trials

Clinical Trials (208)

Showing 20 of 20 trials
NCT06547788Not ApplicableNot Yet RecruitingPrimary

LEFT ATRIAL MONITORING IN PATIENTS BEFORE AND AFTER MITRAL SURGERY - LAMBDA STUDY

NCT05298124Not ApplicableRecruiting

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

NCT04960280Not ApplicableCompleted

A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease

NCT07543874Not Yet RecruitingPrimary

MITRAClip GENeration 5 Mitral Valve Transcatheter Edge-to-Edge Repair Registry

NCT03292497Not ApplicableActive Not RecruitingPrimary

Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation

NCT07086534Not ApplicableRecruitingPrimary

A Clinical Study of GeminiOne TEER System for the Treatment of Severe, Symptomatic MR.

NCT02924363CompletedPrimary

Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study

NCT07366723Not ApplicableActive Not Recruiting

The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation

NCT03706833Not ApplicableActive Not Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

NCT05061004Not ApplicableRecruitingPrimary

Cephea Early Feasibility Study

NCT07517588Not ApplicableNot Yet RecruitingPrimary

EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)

NCT03339115Not ApplicableActive Not RecruitingPrimary

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System

NCT03433274Not ApplicableActive Not RecruitingPrimary

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

NCT07069673RecruitingPrimary

Abbott Cephea Mitral Valve Disease Registry

NCT07007143Phase 4RecruitingPrimary

STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication for Oral Anticoagulant

NCT06901466Phase 4RecruitingPrimary

STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for Oral Anticoagulant

NCT06099665Not ApplicableCompleted

Addressing Under-treatment and Health Equity in AS and MR Using an Integrated EHR Platform

NCT07450911Phase 1RecruitingPrimary

A Clinical Study Evaluating the Replacement of the Native Mitral Valve Using the ReValve System

NCT04153292Not ApplicableRecruitingPrimary

The ENCIRCLE Trial

NCT07409285Not Yet RecruitingPrimary

The EMBRACE Registry: European Post-Market Registry for Catheter Based Mitral Valve Replacement

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Research Network

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