Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.1%

2 terminated out of 18 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed with results

Key Signals

67% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (2)
Early P 1 (1)
P 1 (5)
P 2 (6)

Trial Status

Recruiting6
Completed4
Not Yet Recruiting3
Active Not Recruiting2
Terminated2
Withdrawn1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT06362369Phase 1Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

NCT07450612Recruiting

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

NCT07385846Phase 1Not Yet Recruiting

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

NCT07369986Phase 2Not Yet Recruiting

Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer

NCT03228667Phase 2Active Not Recruiting

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

NCT03452774Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

NCT06215677Not ApplicableRecruiting

Neoadjuvant Immunotherapy for T4 dMMR Colon Cancer

NCT03935893Phase 2Recruiting

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

NCT02983578Phase 2Active Not Recruiting

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

NCT05257057Completed

Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome

NCT04906382Early Phase 1Terminated

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

NCT06034860Phase 1Terminated

Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types

NCT06549855Not ApplicableNot Yet Recruiting

PD-1 Inhibitor Combined With Progesterone Treatment in FST for Patients With MMRd Endometrial Cancer

NCT05729646Phase 2Recruiting

Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

NCT03053466Phase 1Completed

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

NCT04001101Phase 2Withdrawn

Anti-PD-1 +/- RT for MSI-H Solid Tumors

NCT03652077Phase 1Completed

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

NCT04482608Completed

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Showing all 18 trials

Research Network

Activity Timeline