Key Insights

Highlights

Success Rate

43% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

22.2%

4 terminated out of 18 trials

Success Rate

42.9%

-43.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

167%

5 of 3 completed with results

Key Signals

5 with results43% success

Data Visualizations

Phase Distribution

14Total
P 1 (8)
P 2 (6)

Trial Status

Active Not Recruiting7
Terminated4
Completed3
Withdrawn2
Not Yet Recruiting1
Unknown1

Trial Success Rate

42.9%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT04616183Phase 1Active Not Recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

NCT04017650Phase 1Active Not Recruiting

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

NCT05308446Phase 2Active Not Recruiting

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

NCT02874885Active Not Recruiting

Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

NCT04109924Phase 2Completed

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

NCT04362839Phase 1Completed

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

NCT04599140Phase 1Active Not Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

NCT05627635Phase 1Active Not Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

NCT06929338Not Yet Recruiting

xDRIVE in Metastatic Colorectal Cancer

NCT03765736Terminated

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

NCT06575725Phase 2Withdrawn

Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer

NCT05356897Phase 2Withdrawn

Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

NCT05130060Phase 1Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

NCT03300544Phase 1Terminated

Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer

NCT03992456Phase 2Active Not Recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

NCT03592641Phase 2Terminated

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

NCT05185557UnknownPrimary

BRIANSTORM - Early Identification of Patients With Brain Metastases

NCT04044430Phase 1Terminated

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Showing all 18 trials

Research Network

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