Key Insights

Highlights

Success Rate

54% trial completion

Published Results

30 trials with published results (38%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

23.1%

18 terminated out of 78 trials

Success Rate

53.8%

-32.7% vs benchmark

Late-Stage Pipeline

6%

5 trials in Phase 3/4

Results Transparency

143%

30 of 21 completed with results

Key Signals

30 with results54% success18 terminated

Data Visualizations

Phase Distribution

71Total
Not Applicable (8)
Early P 1 (2)
P 1 (24)
P 2 (32)
P 3 (3)
P 4 (2)

Trial Status

Completed21
Active Not Recruiting20
Terminated18
Recruiting13
Unknown3
Withdrawn3

Trial Success Rate

53.8%

Benchmark: 86.6%

Based on 21 completed trials

Clinical Trials (78)

Showing 20 of 20 trials
NCT06305598Phase 1Active Not Recruiting

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

NCT02893917Phase 2Active Not Recruiting

Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer

NCT03517969Phase 2Active Not Recruiting

M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

NCT04550494Phase 2Active Not Recruiting

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT04267887Phase 2Active Not Recruiting

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

NCT00942331Phase 3Completed

Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer

NCT04423211Phase 3Recruiting

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

NCT05398302Phase 1Recruiting

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

NCT04592237Phase 2Active Not Recruiting

Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

NCT05045066Early Phase 1Recruiting

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

NCT03873805Phase 1Active Not Recruiting

PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer

NCT03012321Phase 2Active Not Recruiting

Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT04388852Phase 1Active Not Recruiting

DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers

NCT04716725Phase 2Terminated

68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer

NCT05627219RecruitingPrimary

Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

NCT04314401Active Not Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

NCT03123978Phase 1CompletedPrimary

Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer

NCT03217747Phase 1Active Not Recruiting

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

NCT03218826Phase 1Completed

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

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