Key Insights

Highlights

Success Rate

43% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

12.1%

4 terminated out of 33 trials

Success Rate

42.9%

-43.7% vs benchmark

Late-Stage Pipeline

12%

4 trials in Phase 3/4

Results Transparency

167%

5 of 3 completed with results

Key Signals

5 with results43% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (1)
P 1 (8)
P 2 (17)
P 3 (4)

Trial Status

Recruiting13
Active Not Recruiting7
Terminated4
Completed3
Not Yet Recruiting2
Withdrawn2

Trial Success Rate

42.9%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT03317392Phase 1Active Not Recruiting

Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis

NCT05113537Phase 1Recruiting

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT04471974Phase 2Active Not Recruiting

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT05689021Phase 2Terminated

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

NCT06039371Phase 2Recruiting

Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

NCT06931340Phase 3Recruiting

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

NCT07200830Phase 3Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

NCT06236139Phase 1Recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

NCT07650240Phase 2Not Yet Recruiting

Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial

NCT04190446Phase 2Active Not RecruitingPrimary

A Study To Evaluate Hypofractionated Proton Therapy Or IMRT For Recurrent, Oligometastatic Prostate Cancer

NCT05168618Phase 2Recruiting

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT06982222Phase 1Not Yet Recruiting

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

NCT06616155Phase 1Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT04754425Phase 2Terminated

Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer

NCT04704505Phase 2Recruiting

Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT04455750Phase 3Active Not Recruiting

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

NCT03902951Phase 2Active Not RecruitingPrimary

Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer

NCT04734730Phase 2Recruiting

Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

NCT06145633Phase 2Recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

NCT04616547Phase 2Terminated

Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones

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