Key Insights

Highlights

Success Rate

62% trial completion

Published Results

12 trials with published results (21%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

13.8%

8 terminated out of 58 trials

Success Rate

61.9%

-24.7% vs benchmark

Late-Stage Pipeline

10%

6 trials in Phase 3/4

Results Transparency

92%

12 of 13 completed with results

Key Signals

12 with results62% success

Data Visualizations

Phase Distribution

56Total
Not Applicable (1)
Early P 1 (2)
P 1 (29)
P 2 (18)
P 3 (6)

Trial Status

Recruiting17
Completed13
Active Not Recruiting9
Terminated8
Not Yet Recruiting4
Withdrawn4

Trial Success Rate

61.9%

Benchmark: 86.6%

Based on 13 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT07490301Phase 2RecruitingPrimary

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

NCT06608927Phase 3Active Not RecruitingPrimary

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

NCT06989437Phase 2Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

NCT07619521Phase 1Recruiting

Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal Adenocarcinoma

NCT06445062Phase 1Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

NCT07096362Phase 2RecruitingPrimary

Utility of ctDNA in Early Switch of First-line Chemotherapy in Metastatic Pancreatic Ductal Adenocarcinoma

NCT05558982Phase 2Active Not RecruitingPrimary

BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

NCT05685602Phase 1SuspendedPrimary

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

NCT06390059Phase 2CompletedPrimary

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

NCT04005690Early Phase 1Recruiting

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

NCT04493060Phase 2CompletedPrimary

Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer

NCT07640295Phase 1RecruitingPrimary

Study of JAB-23E73 in Combination With Chemotherapy in Participants With Metastatic PDAC Harboring KRAS Gene Alterations

NCT06843551Phase 2RecruitingPrimary

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

NCT07214298Phase 1RecruitingPrimary

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

NCT05737615Phase 1Withdrawn

PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9

NCT06168812Phase 2Active Not Recruiting

A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer

NCT07733050Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Serplulimab in Combination With Bevacizumab and FOLFIRINOX or NALIRIFOX as Second-Line Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

NCT04809766Phase 1TerminatedPrimary

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

NCT02600949Phase 1Enrolling By Invitation

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

NCT05630183Phase 2CompletedPrimary

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

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