Key Insights

Highlights

Success Rate

60% trial completion

Published Results

11 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

14.5%

8 terminated out of 55 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

11%

6 trials in Phase 3/4

Results Transparency

92%

11 of 12 completed with results

Key Signals

11 with results60% success

Data Visualizations

Phase Distribution

53Total
Not Applicable (1)
Early P 1 (2)
P 1 (27)
P 2 (17)
P 3 (6)

Trial Status

Recruiting16
Completed12
Active Not Recruiting10
Terminated8
Not Yet Recruiting4
Withdrawn4

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (55)

Showing 20 of 20 trials
NCT06608927Phase 3Active Not RecruitingPrimary

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

NCT06989437Phase 2Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

NCT06648434Phase 1RecruitingPrimary

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

NCT07214298Phase 1RecruitingPrimary

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

NCT06390059Phase 2CompletedPrimary

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

NCT05685602Phase 1RecruitingPrimary

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

NCT02600949Phase 1Recruiting

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

NCT06445062Phase 1Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

NCT06904378Phase 1RecruitingPrimary

ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma

NCT05039177Phase 1Completed

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

NCT07490301Phase 2Not Yet RecruitingPrimary

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

NCT06917079Phase 1Recruiting

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

NCT07089940Early Phase 1Recruiting

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

NCT07475234Phase 1Not Yet RecruitingPrimary

Rimegepant Combined With AG Chemotherapy As First-Line Treatment For Metastatic Pancreatic Ductal Adenocarcinoma

NCT06646055Phase 1Active Not RecruitingPrimary

AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer

NCT07445295Phase 3Not Yet RecruitingPrimary

Chiauranib Plus PD-1 Inhibitor, Albumin-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

NCT04005690Early Phase 1Recruiting

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

NCT05642962Phase 1Active Not RecruitingPrimary

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

NCT04666740Phase 2Active Not RecruitingPrimary

A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy

NCT05558982Phase 2Active Not RecruitingPrimary

BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

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