Key Insights

Highlights

Success Rate

30% trial completion

Published Results

14 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

10.8%

7 terminated out of 65 trials

Success Rate

30.0%

-56.5% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

467%

14 of 3 completed with results

Key Signals

14 with results30% success

Data Visualizations

Phase Distribution

62Total
Not Applicable (2)
Early P 1 (1)
P 1 (36)
P 2 (19)
P 3 (3)
P 4 (1)

Trial Status

Active Not Recruiting23
Recruiting22
Terminated7
Withdrawn4
Not Yet Recruiting4
Completed3

Trial Success Rate

30.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (65)

Showing 20 of 20 trials
NCT07017829Phase 2Recruiting

GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer

NCT03025256Phase 1Recruiting

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT06500455Phase 3Recruiting

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

NCT02498613Phase 2Active Not Recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

NCT04250545Phase 1Active Not Recruiting

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

NCT02589522Phase 1Active Not Recruiting

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

NCT02971501Phase 2Active Not RecruitingPrimary

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

NCT05786924Phase 1Recruiting

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

NCT07012031Phase 1Recruiting

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

NCT06982222Phase 1Not Yet Recruiting

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

NCT02496663Phase 1Active Not RecruitingPrimary

Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor

NCT03831932Phase 1Active Not Recruiting

Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer

NCT02503722Phase 1Active Not RecruitingPrimary

Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer

NCT02888743Phase 2Active Not Recruiting

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

NCT04762199Phase 1Recruiting

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

NCT04197934Phase 1Active Not Recruiting

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

NCT06943664Phase 2Not Yet Recruiting

Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT04007744Phase 1Active Not Recruiting

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

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