Key Insights

Highlights

Success Rate

45% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

20.0%

6 terminated out of 30 trials

Success Rate

45.5%

-41.1% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

120%

6 of 5 completed with results

Key Signals

6 with results45% success

Data Visualizations

Phase Distribution

28Total
Early P 1 (1)
P 1 (11)
P 2 (13)
P 3 (3)

Trial Status

Recruiting10
Terminated6
Completed5
Not Yet Recruiting3
Active Not Recruiting3
Withdrawn1

Trial Success Rate

45.5%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (31)

Showing 20 of 20 trials
NCT07576725Phase 2Not Yet Recruiting

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

NCT07011719Phase 3RecruitingPrimary

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

NCT05361720Phase 2Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

NCT06059014Phase 1CompletedPrimary

Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer

NCT04388852Phase 1Active Not Recruiting

DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers

NCT07488572Phase 2Enrolling By Invitation

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

NCT04904302Phase 2Terminated

Sitravatinib and Nivolumab for the Treatment of Metastatic or Advanced Clear Cell Renal Cell Cancer

NCT06349642Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

NCT05122546Phase 1Active Not Recruiting

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

NCT05012371Phase 2Active Not Recruiting

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

NCT07128680Phase 1Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

NCT07383441Phase 3Not Yet Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

NCT03260504Phase 1Terminated

Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer

NCT04370509Phase 2TerminatedPrimary

Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery

NCT07218692Phase 2Not Yet Recruiting

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

NCT07179770Phase 1RecruitingPrimary

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

NCT04510597Phase 3RecruitingPrimary

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

NCT06866262Phase 1Recruiting

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

NCT06361810Phase 1Withdrawn

PSMA Therapy and Immunotherapy in Kidney Cancer

NCT06942104Phase 1Recruiting

Imaging of Solid Tumors Using 18F-TRX

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