Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

7.1%

1 terminated out of 14 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

14%

2 trials in Phase 3/4

Results Transparency

0%

0 of 1 completed with results

Key Signals

50% success

Data Visualizations

Phase Distribution

11Total
Not Applicable (1)
P 1 (3)
P 2 (5)
P 3 (2)

Trial Status

Recruiting7
Withdrawn2
Enrolling By Invitation1
Not Yet Recruiting1
Completed1
Terminated1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT06836609Phase 1Recruiting

A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)

NCT06939816Phase 2Terminated

Vonafexor in Patients With Impaired Renal Function and Suspected MASH (Metabolic Dysfunction-associated Steatohepatitis)

NCT07288138Phase 2RecruitingPrimary

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

NCT07239167Enrolling By Invitation

A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change

NCT07462455Phase 1Not Yet RecruitingPrimary

Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic(PK/PD) Profile of ACT500 in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD)

NCT06465186Phase 2Active Not Recruiting

A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

NCT07334080Phase 1RecruitingPrimary

ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants

NCT06868992Recruiting

Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA

NCT06920043Phase 2RecruitingPrimary

A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

NCT06138821Not ApplicableRecruiting

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NCT06594523Phase 3Withdrawn

A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis

NCT06692283Phase 3Withdrawn

A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASLD and MASH

NCT06342947Phase 2Completed

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD)

NCT06813508Recruiting

Prognostic Factors for HCC and Liver Transplantation in Patients With MASLD/MASH

Showing all 14 trials

Research Network

Activity Timeline