Key Insights

Highlights

Success Rate

64% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.9%

4 terminated out of 31 trials

Success Rate

63.6%

-22.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed with results

Key Signals

2 with results64% success

Data Visualizations

Phase Distribution

25Total
Not Applicable (3)
P 1 (12)
P 2 (10)

Trial Status

Recruiting12
Completed7
Terminated4
Active Not Recruiting3
Unknown2
Not Yet Recruiting1

Trial Success Rate

63.6%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (31)

Showing 20 of 20 trials
NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT06251310Phase 1Recruiting

SW-682 in Advanced Solid Tumors

NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT07126509Not ApplicableRecruiting

Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

NCT05568680Phase 1Recruiting

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

NCT05136677Phase 2CompletedPrimary

A Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin for Unresectable Pleural Mesothelioma in Chinese Participants

NCT05380713Phase 2CompletedPrimary

......SMARTEST Trial......

NCT03907852Phase 1Active Not Recruiting

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

NCT05451849Phase 1Active Not Recruiting

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

NCT04031469Suspended

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

NCT06299163Phase 1Terminated

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

NCT06057935Phase 2Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

NCT05944237Phase 1Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

NCT04214015Withdrawn

A Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma

NCT05188859Phase 2RecruitingPrimary

First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesothelioma

NCT04104776Phase 1Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT05455424Phase 2CompletedPrimary

Niraparib Efficacy in Patient With Unresectable Mesothelioma

NCT06946498Not ApplicableRecruiting

First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.

NCT05324436CompletedPrimary

A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)

NCT03546426Phase 1Active Not RecruitingPrimary

Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies

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