Key Insights

Highlights

Success Rate

81% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.1%

3 terminated out of 37 trials

Success Rate

81.3%

-5.3% vs benchmark

Late-Stage Pipeline

11%

4 trials in Phase 3/4

Results Transparency

23%

3 of 13 completed with results

Key Signals

3 with results81% success

Data Visualizations

Phase Distribution

26Total
Not Applicable (5)
Early P 1 (4)
P 1 (3)
P 2 (10)
P 3 (2)
P 4 (2)

Trial Status

Completed13
Recruiting12
Not Yet Recruiting5
Terminated3
Unknown2
Active Not Recruiting2

Trial Success Rate

81.3%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT04571658Not ApplicableRecruiting

NEPTUNE Match Study

NCT07389499Early Phase 1Not Yet Recruiting

A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney Diseases

NCT07535138Early Phase 1Not Yet RecruitingPrimary

Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy

NCT02199145Not ApplicableCompletedPrimary

Role of Anti-mouse PLA2R1 ELISA in Membranous Nephropathy

NCT06242327RecruitingPrimary

An Outcome Analysis of Primary Membranous Nephropathy

NCT06994468Not ApplicableCompletedPrimary

Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous Nephropathy

NCT04095156RecruitingPrimary

Autoreactive B Cells in Membranous Nephropathy

NCT05894512CompletedPrimary

Analysis of T- and B-Cell Subpopulations in Membranous Nephropathy

NCT07416942Not Yet RecruitingPrimary

Omics of Rituximab-resistance

NCT03949855Phase 2RecruitingPrimary

Belimumab With Rituximab for Primary Membranous Nephropathy

NCT04652570Phase 1TerminatedPrimary

Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy

NCT05505500Recruiting

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

NCT07038382Phase 2RecruitingPrimary

A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis

NCT05732402Phase 1Active Not Recruiting

An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases

NCT06341205Phase 3RecruitingPrimary

Personalized Rituximab Treatment Based on Artificial Intelligence in Membranous Nephropathy (iRITUX)

NCT05050214Phase 2Active Not RecruitingPrimary

Obinutuzumab in Primary MN

NCT01209000Recruiting

Nephrotic Syndrome Study Network

NCT04893096Phase 2CompletedPrimary

MOR202 for Refractory MN

NCT03453619Phase 2Completed

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

NCT04733040Phase 2Completed

Efficacy, Safety and PK/PD of MOR202 in Anti-PLA2R+ Membranous Nephropathy (aMN) (NewPLACE)

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