Key Insights

Highlights

Success Rate

33% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

33.3%

-53.2% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

200%

2 of 1 completed with results

Key Signals

2 with results33% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (4)
P 2 (10)
P 3 (1)

Trial Status

Recruiting11
Active Not Recruiting3
Unknown2
Terminated2
Not Yet Recruiting2
Completed1

Trial Success Rate

33.3%

Benchmark: 86.6%

Based on 1 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07750067Phase 2RecruitingPrimary

Tunlametinib in Combination With Pucotenlimab and Hydroxychloroquine in NRAS Mutant Melanoma

NCT07686835Phase 2Recruiting

Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.

NCT06889610Phase 2Recruiting

A Phase II Clinical Study of Multimodal Ablation Combined With Systemic Drug Therapy for Advanced Solid Tumors.

NCT07651618Phase 2Not Yet Recruiting

A Phase II Trial of Tumour Infiltrating Lymphocyte Adoptive Cell Therapy in Patients With Immune Checkpoint Inhibitor Resistant Unresectable or Metastatic Melanoma

NCT06889766Phase 1Recruiting

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

NCT06767306Phase 2RecruitingPrimary

Stereotactic Ablative Radiotherapy (XRT) and Immunotherapy for Oligometastatic Extracranial Melanoma

NCT07076550Phase 1RecruitingPrimary

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

NCT07442292Not Yet Recruiting

PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor

NCT07376317Phase 2Active Not RecruitingPrimary

Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS)

NCT06784648Phase 1Active Not RecruitingPrimary

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

NCT06880198Not ApplicableRecruitingPrimary

Study to Evaluate Impact® as Support to Anti PD1 or Anti PD1 Based Regimen Treatment in Patients With Inoperable Locally Advanced or Metastatic Melanoma

NCT07050940Not ApplicableRecruitingPrimary

Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naïve, Cutaneous Melanoma Study

NCT06784778RecruitingPrimary

Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.

NCT05732805Phase 3Active Not Recruiting

A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma

NCT06783270Phase 1RecruitingPrimary

T-cell Therapy with CRISPR PD1-edited Tumor Infiltrating Lymphocytes for Patients with Metastatic Melanoma

NCT06586593RecruitingPrimary

Neoadjuvant Immunotherapy of Operable Metastatic Melanoma in Real Life (GCC)

NCT03879395Completed

Surgery for Gastrointestinal Metastases of Malignant Melanoma - a Single Center Retrospective Cohort Study

NCT03913923Phase 2Unknown

Study of Efficacy and Safety of BCD-217 (Anti-CTLA-4 and Anti-PD-1) Followed By BCD-100 (Anti-PD-1) Versus BCD-100 Monotherapy as First-Line Treatment in Patients With Unresectable or Metastatic Melanoma

NCT03514901Phase 2UnknownPrimary

To Evaluate the Efficacy Beyond Progression of Vemurafenib+Cobimetinib Associated With Local Treatment Compared to Second-line Treatment in Patients With BRAFV600+ Metastatic Melanoma in Focal Progression With First-line+Vemurafenib+Cobimetinib.

NCT01702896Phase 2TerminatedPrimary

Interleukin-2 in Metastatic Melanoma

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