Key Insights

Highlights

Success Rate

82% trial completion

Published Results

29 trials with published results (21%)

Research Maturity

60 completed trials (43% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.2%

13 terminated out of 141 trials

Success Rate

82.2%

-4.4% vs benchmark

Late-Stage Pipeline

6%

9 trials in Phase 3/4

Results Transparency

48%

29 of 60 completed with results

Key Signals

29 with results82% success13 terminated

Data Visualizations

Phase Distribution

119Total
Not Applicable (7)
Early P 1 (1)
P 1 (51)
P 2 (51)
P 3 (9)

Trial Status

Completed60
Recruiting32
Unknown17
Terminated13
Active Not Recruiting7
Not Yet Recruiting7

Trial Success Rate

82.2%

Benchmark: 86.5%

Based on 60 completed trials

Clinical Trials (141)

Showing 20 of 20 trials
NCT07702578Phase 3Recruiting

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

NCT05473910Phase 1Recruiting

A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

NCT01861106Phase 2Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

NCT05554835Recruiting

Global Registry and Natural History Study for Mitochondrial Disorders

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT07575412Phase 2Not Yet Recruiting

SHR2554/AZA + Overlapped Modified BUCY for High-risk/Relapsed Leukemia/MDS

NCT07387354Phase 1Not Yet Recruiting

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

NCT05177211Phase 2Completed

Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)

NCT05285813Phase 2Terminated

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

NCT04806906Phase 2CompletedPrimary

Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients

NCT05829226Phase 1Completed

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

NCT07562568Phase 2Not Yet Recruiting

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

NCT02872662CompletedPrimary

Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT

NCT07493538Phase 2Recruiting

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

NCT05582902Active Not RecruitingPrimary

Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients

NCT04547049Phase 3Active Not Recruiting

A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

NCT07081087Recruiting

Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients

NCT05796570Phase 2Recruiting

A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies

NCT04644016Phase 2Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

NCT05226455Phase 1Active Not RecruitingPrimary

Venetoclax in Patients With MDS or AML in Relapse After AHSCT

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