Key Insights

Highlights

Success Rate

67% trial completion

Published Results

37 trials with published results (26%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

16.0%

23 terminated out of 144 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

7%

10 trials in Phase 3/4

Results Transparency

80%

37 of 46 completed with results

Key Signals

37 with results67% success23 terminated

Data Visualizations

Phase Distribution

129Total
Not Applicable (3)
Early P 1 (2)
P 1 (57)
P 2 (57)
P 3 (10)

Trial Status

Completed46
Recruiting44
Terminated23
Active Not Recruiting18
Withdrawn6
Unknown4

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 46 completed trials

Clinical Trials (144)

Showing 20 of 20 trials
NCT03474744Phase 2Active Not RecruitingPrimary

Copanlisib and Rituximab in Marginal Zone Lymphoma Patients

NCT03322865Phase 2Active Not RecruitingPrimary

Obinutuzumab in Marginal Zone Lymphoma

NCT04542824Phase 1Active Not Recruiting

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

NCT06125028Phase 3TerminatedPrimary

[68Ga]Ga-PentixaFor-PET Imaging for Staging of Marginal Zone Lymphoma

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT05100862Phase 3Recruiting

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

NCT05294731Phase 1Recruiting

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

NCT04491370Phase 1Recruiting

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

NCT06544265Phase 1Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT04433156Phase 2CompletedPrimary

VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma

NCT04911478Active Not Recruiting

Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells

NCT03697512Phase 2Active Not RecruitingPrimary

MALIBU Trial - Combination of Ibrutinib and Rituximab in Untreated Marginal Zone Lymphomas

NCT06533579Phase 1Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT02952508Phase 2Active Not Recruiting

Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom

NCT06026319Phase 1Recruiting

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

NCT05783596Phase 2Active Not Recruiting

Glofit and Obin in Follicular Lymphoma and Marginal Zone Lymphoma

NCT06510309Phase 2Recruiting

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

NCT02339922Phase 2Active Not Recruiting

Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma

NCT07441993Phase 2RecruitingPrimary

Exploratory Study of Orelabrutinib in the Treatment of Early-stage Untreated MZL

NCT06151730Recruiting

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

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