Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

17.6%

3 terminated out of 17 trials

Success Rate

76.9%

-9.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

60%

6 of 10 completed with results

Key Signals

6 with results77% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (1)
P 1 (9)
P 2 (5)

Trial Status

Completed10
Terminated3
Active Not Recruiting2
Unknown1
Withdrawn1

Trial Success Rate

76.9%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT06254495Phase 1Active Not Recruiting

A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers

NCT02568267Phase 2Active Not Recruiting

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

NCT06120504Phase 1Terminated

A Safety Study of PF-08046045/SGN-35T in Adults With Advanced Cancers

NCT05106192Not ApplicableWithdrawn

Triamcinolone Acetonide Injections in Primary Cutaneous Lymphoma Plaques With a Novel Needle-free Drug-delivery System.

NCT03942263Completed

A Study to Describe Treatment Patterns and Disease Control in Participants With cHL and sALCL in Routine Clinical Practice in the Russian Federation

NCT04644315Phase 2Terminated

A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors

NCT03049449Phase 1CompletedPrimary

T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas

NCT01449461Phase 1CompletedPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)

NCT02939014Phase 2Completed

Brentuximab Vedotin in Chinese Participants With Relapsed/Refractory CD30-Positive Hodgkin Lymphoma (HL) or Systemic Anaplastic Large Cell Lymphoma (sALCL)

NCT01196208Unknown

A Treatment-Option Protocol to Provide Brentuximab Vedotin to Eligible Patients Completing Studies SGN35-005 or C25001

NCT01309789Phase 1CompletedPrimary

A Phase 1 Study of Brentuximab Vedotin Given Sequentially and Combined With Multi-Agent Chemotherapy for CD30-Positive Mature T-Cell and NK-Cell Neoplasms

NCT00866047Phase 2CompletedPrimary

A Phase 2 Open Label Trial of Brentuximab Vedotin (SGN-35) for Systemic Anaplastic Large Cell Lymphoma

NCT00947856Phase 2Completed

A Brentuximab Vedotin Trial for Patients Who Have Previously Participated in a Brentuximab Vedotin Study

NCT00649584Phase 1Terminated

A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies

NCT00430846Phase 1Completed

Phase I Open-Label Dose Finding Study of SGN-35 for CD30 Positive Hematologic Malignancies

NCT01026415Phase 1Completed

Clinical Pharmacology Study of Brentuximab Vedotin (SGN-35)

NCT01026233Phase 1Completed

Cardiac Safety Study of Brentuximab Vedotin (SGN-35)

Showing all 17 trials

Research Network

Activity Timeline