Key Insights

Highlights

Success Rate

83% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.9%

5 terminated out of 63 trials

Success Rate

82.8%

-3.7% vs benchmark

Late-Stage Pipeline

14%

9 trials in Phase 3/4

Results Transparency

21%

5 of 24 completed with results

Key Signals

5 with results83% success

Data Visualizations

Phase Distribution

51Total
Not Applicable (7)
Early P 1 (2)
P 1 (12)
P 2 (21)
P 3 (6)
P 4 (3)

Trial Status

Completed24
Recruiting18
Active Not Recruiting6
Terminated5
Unknown5
Not Yet Recruiting3

Trial Success Rate

82.8%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (63)

Showing 20 of 20 trials
NCT07570368Not ApplicableNot Yet Recruiting

Targeting Stress-Driven Inflammatory and Angiogenic Pathways With Brief ACT to Enhance Neoadjuvant Chemotherapy Response in Locally Advanced Breast Cancer

NCT06727773Phase 2Recruiting

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

NCT01042379Phase 2Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT07347600RecruitingPrimary

A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer

NCT06827236Phase 1RecruitingPrimary

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

NCT07085767Phase 3Recruiting

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

NCT05744375Phase 2TerminatedPrimary

Trastuzumab Deruxtecan in First-line HER2-positive Locally Advanced/MBC Patients Resistant to Trastuzumab+Pertuzumab

NCT05963997Phase 1Completed

A Study of Samuraciclib and Elacestrant in Participants With Metastatic or Locally Advanced HR+/HER2-negative Breast Cancer

NCT03255577Not ApplicableActive Not Recruiting

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer

NCT06449222Phase 2Active Not RecruitingPrimary

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

NCT03978663Not ApplicableActive Not Recruiting

Three Fraction Radiation to Induce Immuno-Oncologic Response

NCT05383196Phase 1Active Not Recruiting

Onvansertib + Paclitaxel In TNBC

NCT06064812Phase 1Recruiting

A Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC.

NCT05415215Phase 3Completed

A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer

NCT07386938Phase 3Active Not RecruitingPrimary

A Study of the Efficacy, Safety and Pharmacokinetics of RPH-051 and Perjeta® in Combination With Trastuzumab and Docetaxel as the 1st Line Therapy in Patients With HER2-positive Breast Cancer

NCT07024173Phase 3RecruitingPrimary

A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

NCT04360941Phase 1Recruiting

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

NCT06220214Early Phase 1Recruiting

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

NCT03685331Phase 1Completed

HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer

NCT07307287Phase 2Not Yet Recruiting

SHR-A1811 Plus Pertuzumab as Neoadjuvant Therapy for Early or Locally Advanced HR-Positive HER2-Positive Breast Cancer: A Prospective, Open-Label, Phase II Study

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