Key Insights

Highlights

Success Rate

64% trial completion

Published Results

11 trials with published results (38%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

31.0%

9 terminated out of 29 trials

Success Rate

64.0%

-22.5% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

69%

11 of 16 completed with results

Key Signals

11 with results64% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (5)
P 1 (8)
P 2 (13)
P 3 (3)

Trial Status

Completed16
Terminated9
Unknown2
Recruiting1
Withdrawn1

Trial Success Rate

64.0%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT03578367Phase 2Completed

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Who Have Been Previously Treated With Imatinib and Have Not Achieved Deep Molecular Response.

NCT04260022Phase 1RecruitingPrimary

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

NCT02269267Phase 2CompletedPrimary

The Life After Stopping Tyrosine Kinase Inhibitors Study (The LAST Study)

NCT00406393Phase 3Completed

Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)

NCT00449761Phase 2TerminatedPrimary

Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase

NCT00176930Not ApplicableTerminatedPrimary

Stem Cell Transplant for Hematological Malignancy

NCT00539656Phase 1Terminated

Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers

NCT00167180Phase 2TerminatedPrimary

Post Transplant Donor Lymphocyte Infusion

NCT00067002Phase 2Completed

Randomized Double Cord Blood Transplant Study

NCT00167167Not ApplicableCompletedPrimary

Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia

NCT00246662Phase 1Completed

Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies

NCT00264160Phase 2CompletedPrimary

Efficacy and Safety of Oral AMN107 in Adults With Chronic Myelogenous Leukemia Resistant and/or Intolerant to Imatinib Mesylate Therapy

NCT00050531Phase 3CompletedPrimary

High-Dose Gleevec Alone or in Combination With Peg-Intron and GM-CSF in Early Phase Chronic Myelogenous Leukemia (CML)

NCT00732186Phase 1WithdrawnPrimary

Study of Ipilimumab and Dasatinib Combination Therapy in Patients With Chronic or Accelerated Chronic Myeloid Leukemia

NCT00538109Not ApplicableCompletedPrimary

An Open-Label, Multicenter, Expanded Access Study of Oral AMN 107 in Adult Patients With Imatinib (Glivec®/Gleevec®_ - Resistant or Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase

NCT01050946Phase 2Terminated

Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit

NCT00034684Phase 1Completed

Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701)

NCT00320190Phase 2TerminatedPrimary

Study of Dasatinib in Patients With Chronic Phase Chronic Myeloid Leukemia and a Suboptimal Response to Imatinib

NCT00393380Phase 2TerminatedPrimary

Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor

NCT00186342Not ApplicableCompleted

Sibling and Unrelated Donor Hematopoietic Cell Transplant in Hematologic Malignancies

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