Key Insights

Highlights

Success Rate

94% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

2.2%

1 terminated out of 45 trials

Success Rate

94.1%

+7.6% vs benchmark

Late-Stage Pipeline

13%

6 trials in Phase 3/4

Results Transparency

25%

4 of 16 completed with results

Key Signals

4 with results94% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (16)
Early P 1 (1)
P 1 (1)
P 2 (4)
P 3 (3)
P 4 (3)

Trial Status

Completed16
Unknown12
Recruiting10
Not Yet Recruiting4
Active Not Recruiting2
Terminated1

Trial Success Rate

94.1%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (45)

Showing 20 of 20 trials
NCT05316311Not ApplicableCompletedPrimary

A Study of Implantation of CRENEOUS ENTERPRISE 2 Intracranial Stent in Participants With Severe Symptomatic Intracranial Atherosclerotic Stenosis

NCT05515874Phase 4CompletedPrimary

Predicting Stroke Risk in ICAD With Novel MRI

NCT07468448Phase 3Not Yet Recruiting

Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS)

NCT05757505Not ApplicableRecruitingPrimary

The Efficacy and Safety of Intracranial Stent (Tonbridge) in Endovascular Treatment of Symptomatic Intracranial Atherosclerotic Stenosis

NCT07282041Phase 2RecruitingPrimary

Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis

NCT06472336Not ApplicableRecruiting

IntraCranial Atherosclerosis Related Large-vessel Occlusion Treated With Urgent Stenting (ICARUS)

NCT06714526Not ApplicableRecruitingPrimary

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy in Symptomatic ICAD

NCT06336174RecruitingPrimary

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

NCT03084523Phase 1Completed

Treatment Targets for Inflamed Intracranial Atherosclerosis on Vessel Wall MRI

NCT05897645Recruiting

High-resolution Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaques in Ischemic Stroke

NCT06902740Phase 4RecruitingPrimary

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

NCT04010955Active Not Recruiting

Adding Antiplatelet During Edoxaban Treatment in Stroke Patients With Non-valvular Atrial Fibrillation (ADD-ON)

NCT03990545CompletedPrimary

Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke

NCT05001984Phase 2Active Not RecruitingPrimary

Trial of PCSK9 Inhibition in Patients with Acute Stroke and Symptomatic Intracranial Atherosclerosis

NCT06610578RecruitingPrimary

ICAS Screen Based on RIC

NCT06614972Not Yet Recruiting

Balloon-expandable DES for ICAS Registry Study (BDES-ICAS Registry)

NCT04631055Not ApplicableCompletedPrimary

AcoArt sICAS: DCB in the Treatment of Symptomatic Intracranial Atherosclerotic Stenosis

NCT04627870Not ApplicableRecruitingPrimary

ACOART Intracranial ISR Pilot:Intracranial DCB in the Treatment of Intracranial In-stent Restenosis

NCT06453252Not Yet Recruiting

Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

NCT05947994Not ApplicableCompletedPrimary

Elucidate Outcomes of Elective High-grade/Total Occlusion Intracranial Arteries Using Low-profile Self-expanding Stent

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