Key Insights

Highlights

Success Rate

96% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

2.6%

1 terminated out of 39 trials

Success Rate

96.0%

+9.5% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

13%

3 of 24 completed with results

Key Signals

3 with results96% success

Data Visualizations

Phase Distribution

24Total
Not Applicable (12)
Early P 1 (1)
P 1 (4)
P 2 (6)
P 3 (1)

Trial Status

Completed24
Recruiting6
Unknown4
Withdrawn3
Terminated1
Not Yet Recruiting1

Trial Success Rate

96.0%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (39)

Showing 20 of 20 trials
NCT02322177CompletedPrimary

Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol

NCT06839456Phase 1Recruiting

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

NCT00078078Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

NCT02356653Early Phase 1Recruiting

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

NCT04399694Completed

Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders

NCT06573723Recruiting

Institutional Registry of Rare Diseases

NCT02349906Phase 2Completed

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

NCT03548779Not ApplicableCompleted

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

NCT05732922Not ApplicableCompleted

ORCHARD- Optimising Home Assessment of Rural Patients

NCT05818566CompletedPrimary

Orphan Drugs for Inherited Metabolic Diseases

NCT06654765Not Yet RecruitingPrimary

Growth and Development of Children With Inborn Errors of Metabolism in Assiut Governorate

NCT05413278Not ApplicableRecruiting

Targeted Interventions for Successful Transition and Transfer of Adolescents With Inborn Errors of Metabolism to Adult Services

NCT06360913Not ApplicableRecruitingPrimary

Blood Spot and Urine Metabolomic Screening Applied to Rare Diseases

NCT05330039CompletedPrimary

Characterization of Intestinal Microbiota in Children With Inborn Errors of Metabolism (IEM)

NCT03168399Not ApplicableCompleted

Evaluation of PKU Explore

NCT03058848Not ApplicableCompleted

Evaluation of PKU Start

NCT03866954Phase 2Withdrawn

Trial of Erythrocyte Encapsulated Thymidine Phosphorylase In Mitochondrial Neurogastrointestinal Encephalomyopathy

NCT04097275UnknownPrimary

Induced Pluripotent Stem Cells for the Development of Novel Drug Therapies for Inborn Errors of Metabolism (iPSC-IEM)

NCT05437445CompletedPrimary

Utilizing Augmented Artificial Intelligence for Aminoacidopathies

NCT04098198CompletedPrimary

Biomarkers for Inborn Errors of Metabolism

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