Hypereosinophilic Syndrome
26
5
7
12
Key Insights
Highlights
Success Rate
80% trial completion
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 27/100
11.5%
3 terminated out of 26 trials
80.0%
-6.5% vs benchmark
31%
8 trials in Phase 3/4
67%
8 of 12 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 12 completed trials
Clinical Trials (26)
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents
Study in Pediatrics With HypEREosinophilic Syndrome (SPHERE)
A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)
Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome
Natural History of Hypereosinophilia and Hypereosinophilic Syndromes
Identification of New Markers in the Hypereosinophilic Syndrome
Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders
Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme for Subjects With Severe Asthma 112562: Expanded Access for Patients With Hypereosinophilic
Steroid Treatment for Hypereosinophilic Syndrome
Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate
A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies
Phase II Gleevec Idiopathic Hypereosinophilic Syndrome
A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622
Intravenous Mepolizumab In Subjects With Hypereosinophilic Syndromes (HES)
Efficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES)
Eosinophilia Diagnosis
Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome