Key Insights

Highlights

Success Rate

69% trial completion

Published Results

39 trials with published results (48%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

21.0%

17 terminated out of 81 trials

Success Rate

68.5%

-18.0% vs benchmark

Late-Stage Pipeline

9%

7 trials in Phase 3/4

Results Transparency

105%

39 of 37 completed with results

Key Signals

39 with results69% success17 terminated

Data Visualizations

Phase Distribution

80Total
Not Applicable (7)
Early P 1 (3)
P 1 (29)
P 2 (34)
P 3 (6)
P 4 (1)

Trial Status

Completed37
Terminated17
Active Not Recruiting14
Withdrawn6
Recruiting4
Suspended2

Trial Success Rate

68.5%

Benchmark: 86.5%

Based on 37 completed trials

Clinical Trials (81)

Showing 20 of 20 trials
NCT02208375Phase 1Active Not Recruiting

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

NCT02445391Phase 3Active Not Recruiting

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

NCT02115282Phase 3Active Not Recruiting

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

NCT00877500Phase 2Active Not Recruiting

Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy

NCT02488967Phase 3Active Not Recruiting

Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

NCT03633331Phase 2Completed

Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer

NCT02744053Early Phase 1Active Not Recruiting

DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer

NCT02957968Phase 2Active Not Recruiting

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

NCT02398773Phase 2Active Not RecruitingPrimary

FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy

NCT02876107Phase 2Active Not Recruiting

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

NCT03723928Not ApplicableRecruiting

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

NCT01525966Phase 2Active Not Recruiting

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer

NCT03725436Phase 1Completed

ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors

NCT02945579Not ApplicableRecruiting

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

NCT03359954Phase 2Active Not Recruiting

Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer

NCT04090567Phase 2Recruiting

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

NCT02860000Phase 2Completed

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

NCT02993068Not ApplicableSuspended

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

NCT02432963Phase 1Active Not Recruiting

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

NCT02411656Phase 2Active Not Recruiting

Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy

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