Key Insights

Highlights

Success Rate

33% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 85/100

Termination Rate

20.0%

4 terminated out of 20 trials

Success Rate

33.3%

-53.2% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 2 completed with results

Key Signals

33% success

Data Visualizations

Phase Distribution

19Total
P 1 (11)
P 2 (8)

Trial Status

Recruiting4
Terminated4
Unknown4
Active Not Recruiting3
Withdrawn2
Completed2

Trial Success Rate

33.3%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (20)

Showing 20 of 20 trials
NCT04692831Phase 1Active Not Recruiting

Testing a New Imaging Agent to Identify Cancer

NCT05480384Phase 2Active Not Recruiting

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

NCT06695845Phase 2Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT04995003Phase 1Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

NCT05511844Phase 1Terminated

Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors

NCT05868226Phase 1Recruiting

PRE-I-SPY Phase I/Ib Oncology Platform Program

NCT05904730Phase 1Completed

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

NCT04660929Phase 1Active Not Recruiting

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

NCT06187506Phase 2Recruiting

Disitamab Vedotin Combined With BCG Therapy in HER2-expressing High-risk Non-muscle Invasive Bladder Cancer

NCT04602117Phase 1Withdrawn

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

NCT06055153Phase 1Unknown

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

NCT04650451Phase 1Suspended

Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors

NCT05170256Phase 2Unknown

Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients

NCT03630809Phase 2Terminated

Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1

NCT02840110Terminated

Long-Term Follow-Up Study of Subjects Treated With ACTR T Cell Product

NCT04464967Phase 1Withdrawn

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

NCT03613168Phase 2Completed

Trastuzumab in HER2-positive Biliary Tract Cancer

NCT03680560Phase 1Terminated

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

NCT04215159Phase 2UnknownPrimary

Trastuzumab Biosimilar (Samfenet®) Plus Treatment of Physician's Choice (TPC) in Patients With HER2-positive Solid Tumor

NCT04179656Phase 2Unknown

The Basket Study of Pyrotinib Maleate for HER2-Postive Solid Tumor

Showing all 20 trials

Research Network

Activity Timeline