Hemophagocytic Lymphohistiocytosis
37
2
6
8
Key Insights
Highlights
Success Rate
67% trial completion
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 27/100
10.8%
4 terminated out of 37 trials
66.7%
-19.8% vs benchmark
32%
12 trials in Phase 3/4
88%
7 of 8 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 8 completed trials
Clinical Trials (37)
Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis
Comparison of Two Etoposide Initiation Strategies for Severe Hemophagocytic Lymphohistiocytosis
Immune Disorder HSCT Protocol
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma
Administration of Donor T Cells With the Caspase-9 Suicide Gene
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Evaluation of IFNγ and Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis
Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases
Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement
GTP Regimen in the Treatment of Refractory/Recurrent HLH
L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH
Diagnostic Biomarkers for Adult Hemophagocytic Lymphohistiocytosis in Critically Ill Patients (HEMICU)
Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)
Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH
A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody
L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLH
Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)
DEP Combine With PD-1 Antibody as an Treatment for EBV-HLH
Chidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLH