Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.4%

4 terminated out of 54 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

30%

3 of 10 completed with results

Key Signals

3 with results71% success

Data Visualizations

Phase Distribution

53Total
Not Applicable (9)
Early P 1 (1)
P 1 (24)
P 2 (17)
P 3 (2)

Trial Status

Recruiting22
Completed10
Not Yet Recruiting9
Active Not Recruiting5
Terminated4
Withdrawn3

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (54)

Showing 20 of 20 trials
NCT06769698Phase 2RecruitingPrimary

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT05891171Phase 1Active Not Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT07168785Early Phase 1Not Yet RecruitingPrimary

[18F]-AraG PET Imaging in LA HNSCC

NCT06607406Not ApplicableRecruiting

Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

NCT07601737Phase 2Recruiting

Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT06797986Phase 1RecruitingPrimary

A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects With HPV Positive HNSCC.

NCT04083599Phase 1Active Not Recruiting

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

NCT05249426Phase 1CompletedPrimary

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

NCT07462377Phase 1Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

NCT04080804Phase 2Active Not RecruitingPrimary

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

NCT05176483Phase 1Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

NCT07659678Phase 2Not Yet Recruiting

CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma

NCT07517198Phase 1Recruiting

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

NCT04603248Not ApplicableCompletedPrimary

A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT06295731Phase 2Active Not RecruitingPrimary

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

NCT06794372Phase 2RecruitingPrimary

[68Ga]Ga-FAPI-46 in Staging of Head and Neck Carcinomas

NCT06630780Not ApplicableRecruitingPrimary

Reduction of Postoperative Radiotherapy in Head and Neck Squamous Cell Carcinoma

NCT07545967Phase 1RecruitingPrimary

Re-radiotherapy Combined With Chidamide for the Treatment of Recurrent Head and Neck Squamous Cell Carcinoma After Radiotherapy

NCT05985655Phase 1RecruitingPrimary

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

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