Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.7%

4 terminated out of 52 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

38%

3 of 8 completed with results

Key Signals

3 with results67% success

Data Visualizations

Phase Distribution

51Total
Not Applicable (9)
Early P 1 (1)
P 1 (24)
P 2 (15)
P 3 (2)

Trial Status

Recruiting20
Not Yet Recruiting9
Completed8
Active Not Recruiting7
Terminated4
Withdrawn3

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (52)

Showing 20 of 20 trials
NCT04083599Phase 1Active Not Recruiting

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

NCT06794372Phase 2RecruitingPrimary

[68Ga]Ga-FAPI-46 in Staging of Head and Neck Carcinomas

NCT06769698Phase 2RecruitingPrimary

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT05249426Phase 1Active Not RecruitingPrimary

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

NCT06630780Not ApplicableRecruitingPrimary

Reduction of Postoperative Radiotherapy in Head and Neck Squamous Cell Carcinoma

NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT07545967Phase 1RecruitingPrimary

Re-radiotherapy Combined With Chidamide for the Treatment of Recurrent Head and Neck Squamous Cell Carcinoma After Radiotherapy

NCT05985655Phase 1RecruitingPrimary

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

NCT04080804Phase 2Active Not RecruitingPrimary

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

NCT04799054Phase 1Terminated

A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

NCT07517198Phase 1Recruiting

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

NCT06295731Phase 2Active Not RecruitingPrimary

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

NCT05891171Phase 1Active Not Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT07465276Phase 2RecruitingPrimary

Neoadjuvant Ficerafusp Alfa With Pembrolizumab in Resectable SCC

NCT07462377Phase 1Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

NCT07457281Phase 1RecruitingPrimary

GV20-0251 and Sintilimab for Neoadjuvant Treatment of Resectable Head and Neck Squamous Cell Carcinoma: A Single-Arm Study

NCT05176483Phase 1Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

NCT07227168Phase 1RecruitingPrimary

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

NCT04603248Not ApplicableActive Not RecruitingPrimary

A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

NCT07393477Phase 2Not Yet Recruiting

Neoadjuvant Becotatug Vedotin Plus Pucotenlimab and Cisplatin for Locally Advanced Head and Neck Squamous Cell Carcinoma

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