Key Insights

Highlights

Success Rate

72% trial completion

Published Results

61 trials with published results (12%)

Research Maturity

126 completed trials (25% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.9%

49 terminated out of 495 trials

Success Rate

72.0%

-14.6% vs benchmark

Late-Stage Pipeline

5%

25 trials in Phase 3/4

Results Transparency

48%

61 of 126 completed with results

Key Signals

61 with results72% success49 terminated

Data Visualizations

Phase Distribution

454Total
Not Applicable (51)
Early P 1 (17)
P 1 (175)
P 2 (186)
P 3 (22)
P 4 (3)

Trial Status

Recruiting129
Completed126
Active Not Recruiting68
Unknown60
Terminated49
Not Yet Recruiting41

Trial Success Rate

72.0%

Benchmark: 86.6%

Based on 126 completed trials

Clinical Trials (495)

Showing 20 of 20 trials
NCT06251050Phase 1CompletedPrimary

A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy

NCT07667400Phase 1Not Yet Recruiting

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

NCT07552558Phase 1Not Yet RecruitingPrimary

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

NCT05707078Not ApplicableRecruitingPrimary

PET/CT Follow up for Head and Neck Squamous Cell Carcinoma

NCT05859074Phase 1Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

NCT07272642Phase 1Not Yet Recruiting

A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.

NCT05635643Phase 1Active Not Recruiting

Study of CHS-114 in Participants With Advanced Solid Tumors

NCT05544136Phase 2Recruiting

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

NCT06289049Phase 2Completed

Heavy Strength Training in Head and Neck Cancer Survivors

NCT07758621Phase 3Not Yet RecruitingPrimary

SYS6010 vs Investigator's Choice of Monotherapy in Patients With Recurrent or Metastatic HNSCC

NCT05674396Phase 2RecruitingPrimary

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

NCT07744126Phase 2Not Yet RecruitingPrimary

A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT07572864Phase 2RecruitingPrimary

Neoadjuvant ICI and Mitochondrial Vaccine for Resectable HNSCC

NCT05877599Phase 1Recruiting

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

NCT07743723Phase 1Not Yet Recruiting

A Study of IOV-5001 in Adults With Advanced Solid Tumors

NCT07677475Phase 2Not Yet RecruitingPrimary

MRG003 Plus Toripalimab Versus Toripalimab as Neoadjuvant Therapy for PD-L1-Positive, Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT06465069Phase 1Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT06980038Phase 2RecruitingPrimary

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT03258554Phase 2Completed

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

NCT03412058Not ApplicableTerminated

Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists

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