Key Insights

Highlights

Success Rate

70% trial completion

Published Results

56 trials with published results (12%)

Research Maturity

112 completed trials (24% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.9%

47 terminated out of 476 trials

Success Rate

70.4%

-16.1% vs benchmark

Late-Stage Pipeline

5%

24 trials in Phase 3/4

Results Transparency

50%

56 of 112 completed with results

Key Signals

56 with results70% success47 terminated

Data Visualizations

Phase Distribution

435Total
Not Applicable (50)
Early P 1 (17)
P 1 (168)
P 2 (176)
P 3 (21)
P 4 (3)

Trial Status

Recruiting135
Completed112
Active Not Recruiting65
Unknown62
Terminated47
Not Yet Recruiting33

Trial Success Rate

70.4%

Benchmark: 86.5%

Based on 112 completed trials

Clinical Trials (476)

Showing 20 of 20 trials
NCT06980038Phase 2RecruitingPrimary

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT05743569Active Not Recruiting

3D Specimen Maps for RT Planning

NCT06806852Phase 1RecruitingPrimary

A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone

NCT07172256Phase 2Not Yet RecruitingPrimary

CUE-101with Pembrolizumab for LA-HPV+HNSCCs

NCT05877599Phase 1Recruiting

A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

NCT05576974Phase 2Recruiting

A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

NCT06238479Phase 1Active Not Recruiting

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT05913388Phase 2Recruiting

GB1211 and Pembrolizumab Versus Pembrolizumab and Placebo in Patients With Metastatic Melanoma and Head and Neck Squamous Cell Carcinoma

NCT05172258Phase 2Active Not RecruitingPrimary

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

NCT05005403Phase 1Recruiting

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

NCT05420948Phase 2Suspended

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

NCT04938609Phase 2Active Not Recruiting

Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC)

NCT03236935Phase 1Completed

Phase Ib of L-NMMA and Pembrolizumab

NCT05858736Phase 1Active Not Recruiting

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors

NCT05077709Phase 2Completed

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

NCT06451497Phase 1Recruiting

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

NCT07507058Not ApplicableNot Yet RecruitingPrimary

Hypofractionated Radiotherapy for Postoperative Intermediate-Risk Head and Neck Squamous Cell Carcinoma

NCT06147037Phase 1Recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

NCT03370276Phase 1Completed

Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

NCT06870487Phase 1Active Not Recruiting

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers

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