Key Insights

Highlights

Success Rate

86% trial completion

Published Results

12 trials with published results (27%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

8.9%

4 terminated out of 45 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

16%

7 trials in Phase 3/4

Results Transparency

50%

12 of 24 completed with results

Key Signals

12 with results86% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (7)
Early P 1 (1)
P 1 (9)
P 2 (13)
P 3 (7)

Trial Status

Completed24
Not Yet Recruiting8
Recruiting5
Terminated4
Unknown3
Withdrawn1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (45)

Showing 20 of 20 trials
NCT07570407Not Yet Recruiting

Quantification of Peripheral Blood iNKTs After Allogeneic Stem Cell Transplantation

NCT06083129Phase 3RecruitingPrimary

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor

NCT03945591Phase 2CompletedPrimary

High-Dose Post-Transplant Cyclophosphamide and Bortezomib (CyBor) for the Prevention of Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

NCT07302776Phase 1Not Yet RecruitingPrimary

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

NCT06995521Phase 2Not Yet RecruitingPrimary

Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) Population

NCT06590285Not ApplicableRecruitingPrimary

Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation

NCT02891603Phase 1Completed

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

NCT03605927Phase 1Completed

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

NCT02338232Not ApplicableTerminatedPrimary

Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell Transplantation

NCT07508345CompletedPrimary

Endothelial Dysfunction as a Predictive Marker of Acute Graft-Versus-Host Disease in Adult Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

NCT05675930Phase 2Recruiting

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

NCT05544448Not ApplicableCompleted

In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases

NCT07314892Recruiting

Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).

NCT05415410Phase 2TerminatedPrimary

Proof-of-concept Trial of Apraglutide in Acute Graft Versus Host Disease (aGVHD)

NCT03680092Phase 2CompletedPrimary

Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation

NCT04473911Phase 1CompletedPrimary

Haplo Peripheral Blood Sct In GVHD Prevention

NCT05263999Phase 3Terminated

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

NCT07014059Phase 2Not Yet RecruitingPrimary

Autologous Serum Obtained by a Closed-Circuit Collection Device

NCT06938165Not ApplicableCompletedPrimary

The Safety and Efficacy of Fecal Microbiota Transplant (FMT) for Steroid-refractory Graft-versus-host Disease

NCT03763318Phase 1Completed

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD

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