Key Insights

Highlights

Success Rate

84% trial completion

Published Results

36 trials with published results (20%)

Research Maturity

95 completed trials (53% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.1%

18 terminated out of 178 trials

Success Rate

84.1%

-2.4% vs benchmark

Late-Stage Pipeline

15%

27 trials in Phase 3/4

Results Transparency

38%

36 of 95 completed with results

Key Signals

36 with results84% success18 terminated

Data Visualizations

Phase Distribution

144Total
Not Applicable (22)
Early P 1 (1)
P 1 (41)
P 2 (53)
P 3 (17)
P 4 (10)

Trial Status

Completed95
Unknown27
Recruiting20
Terminated18
Active Not Recruiting12
Withdrawn3

Trial Success Rate

84.1%

Benchmark: 86.5%

Based on 95 completed trials

Clinical Trials (178)

Showing 20 of 20 trials
NCT04044365Active Not RecruitingPrimary

Pediatric cGVHD Symptom Scale

NCT06824103Phase 4RecruitingPrimary

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

NCT00186641Phase 2CompletedPrimary

High Dose Chemotherapy and Autologous Transplant for Breast Cancer

NCT00106925Recruiting

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

NCT07569653Phase 4Recruiting

Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT.

NCT05333978Not ApplicableTerminatedPrimary

Optoacoustic Detection of Inflammation Using MSOT Device

NCT07606703Phase 2Recruiting

A Prospective Study of Madecassoside Tablets in Sclerotic Chronic Graft-versus-Host Disease After Allo-HSCT

NCT05531786Phase 1RecruitingPrimary

Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

NCT07364617Phase 2RecruitingPrimary

Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHD

NCT04380740Phase 2RecruitingPrimary

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

NCT06008808Phase 1RecruitingPrimary

Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

NCT03207958Phase 1CompletedPrimary

Belimumab for Prevention of Chronic Graft-versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation

NCT07006506Phase 2Recruiting

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

NCT06160986Not ApplicableActive Not RecruitingPrimary

Horizons Chronic Graft-Versus-Host-Disease Study

NCT04337515Not ApplicableRecruitingPrimary

A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant

NCT02891603Phase 1CompletedPrimary

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

NCT05238155CompletedPrimary

Evaluation of the Impact of Reduced Immunosuppression

NCT01902576Active Not RecruitingPrimary

Chronic GVHD Response Measures Validation

NCT03369353Enrolling By InvitationPrimary

Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)

NCT05236062Not ApplicableRecruitingPrimary

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

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