Key Insights

Highlights

Success Rate

85% trial completion

Published Results

35 trials with published results (20%)

Research Maturity

94 completed trials (53% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

9.7%

17 terminated out of 176 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

15%

26 trials in Phase 3/4

Results Transparency

37%

35 of 94 completed with results

Key Signals

35 with results85% success17 terminated

Data Visualizations

Phase Distribution

142Total
Not Applicable (22)
Early P 1 (1)
P 1 (41)
P 2 (52)
P 3 (17)
P 4 (9)

Trial Status

Completed94
Unknown28
Recruiting18
Terminated17
Active Not Recruiting11
Withdrawn3

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 94 completed trials

Clinical Trials (176)

Showing 20 of 20 trials
NCT00106925Recruiting

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

NCT04337515Not ApplicableRecruitingPrimary

A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant

NCT06160986Not ApplicableActive Not RecruitingPrimary

Horizons Chronic Graft-Versus-Host-Disease Study

NCT07006506Phase 2Recruiting

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

NCT06008808Phase 1RecruitingPrimary

Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

NCT02891603Phase 1CompletedPrimary

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

NCT05531786Phase 1RecruitingPrimary

Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

NCT05238155CompletedPrimary

Evaluation of the Impact of Reduced Immunosuppression

NCT01902576Active Not RecruitingPrimary

Chronic GVHD Response Measures Validation

NCT04044365RecruitingPrimary

Pediatric cGVHD Symptom Scale

NCT03369353Enrolling By InvitationPrimary

Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)

NCT05236062Not ApplicableRecruitingPrimary

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

NCT06649201RecruitingPrimary

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

NCT05617625Phase 2Suspended

CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome

NCT04380740Phase 2RecruitingPrimary

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

NCT02867384Phase 2CompletedPrimary

Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantation

NCT05621759Phase 2Active Not RecruitingPrimary

Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD

NCT05333978Not ApplicableSuspendedPrimary

Optoacoustic Detection of Inflammation Using MSOT Device

NCT03842696Phase 1Active Not Recruiting

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

NCT07365696Recruiting

Fatigue and Cognitive Dysfunction Due to Synaptopathy or Graft Versus Host (GVH) Disease in the Brain.

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