Key Insights

Highlights

Success Rate

79% trial completion

Published Results

57 trials with published results (11%)

Research Maturity

187 completed trials (35% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.0%

49 terminated out of 542 trials

Success Rate

79.2%

-7.3% vs benchmark

Late-Stage Pipeline

3%

17 trials in Phase 3/4

Results Transparency

30%

57 of 187 completed with results

Key Signals

57 with results79% success49 terminated

Data Visualizations

Phase Distribution

392Total
Not Applicable (130)
Early P 1 (32)
P 1 (120)
P 2 (93)
P 3 (14)
P 4 (3)

Trial Status

Completed187
Recruiting127
Unknown87
Terminated49
Not Yet Recruiting35
Active Not Recruiting26

Trial Success Rate

79.2%

Benchmark: 86.6%

Based on 187 completed trials

Clinical Trials (542)

Showing 20 of 20 trials
NCT06355908Phase 1SuspendedPrimary

IL13Rα2 CAR-T for Patients With r/r Glioma

NCT07025226Early Phase 1RecruitingPrimary

Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT06855628Phase 2CompletedPrimary

Assessment of Novel Metabolic Imaging Modalities as A Predictor Of Therapeutic EfficacyiIn Glioblastoma (GBM)

NCT06750458Phase 3CompletedPrimary

Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients

NCT07488780Not ApplicableRecruitingPrimary

Language Network Prehab Via fMRI Neurofeedback

NCT07219199Not ApplicableNot Yet RecruitingPrimary

Residual IDH1-Mutant Tumor Cell Quantification Study

NCT07326566Phase 2Recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

NCT07416188Phase 1Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT07821112Phase 2Not Yet RecruitingPrimary

Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®

NCT05555550Early Phase 1RecruitingPrimary

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

NCT07703436Phase 2Not Yet Recruiting

Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease

NCT06804655Phase 2Recruiting

Pharmacoscopy for Patients With Refractory Primary Brain Tumors

NCT07826949Phase 1Not Yet Recruiting

A Phase 1 Study of SRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma.

NCT04065776Not ApplicableActive Not RecruitingPrimary

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

NCT06101069Not ApplicableRecruiting

Development of MRF for Characterization of Brain Tumors After Radiotherapy

NCT06797661Not ApplicableRecruiting

Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.

NCT07243470Phase 1RecruitingPrimary

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

NCT04373720Not ApplicableRecruitingPrimary

MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas

NCT07814872Not Yet Recruiting

A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment

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