Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.6%

3 terminated out of 22 trials

Success Rate

82.4%

-4.1% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

43%

6 of 14 completed with results

Key Signals

6 with results82% success

Data Visualizations

Phase Distribution

21Total
Early P 1 (2)
P 1 (9)
P 2 (9)
P 3 (1)

Trial Status

Completed14
Withdrawn4
Terminated3
Suspended1

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT04482933Phase 2Withdrawn

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

NCT02709226Phase 1Completed

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

NCT06806228Phase 1Suspended

Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)

NCT01149850Phase 2CompletedPrimary

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

NCT03027388Phase 2Completed

Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

NCT01957956Early Phase 1CompletedPrimary

Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

NCT03360708Early Phase 1CompletedPrimary

Vaccine Therapy in Treating Patients With Recurrent Glioblastoma

NCT02366728Phase 2Completed

DC Migration Study for Newly-Diagnosed GBM

NCT05218408Phase 1Withdrawn

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type

NCT04489420Phase 1Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM

NCT01609790Phase 2CompletedPrimary

Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors

NCT03014804Phase 2WithdrawnPrimary

Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen Vaccine and Nivolumab in Treating Patients With Recurrent Glioblastoma

NCT00943462Withdrawn

Study of 18F-FEC for Positron Emission Tomography-Computed Tomography (PET-CT) Imaging of GBM

NCT01498328Phase 2Completed

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma

NCT01514201Phase 1Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

NCT01836549Phase 2Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

NCT01480479Phase 3Completed

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma

NCT01975116Phase 1Completed

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

NCT01250470Phase 1Completed

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

NCT01082926Phase 1Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

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