Key Insights

Highlights

Success Rate

71% trial completion

Published Results

34 trials with published results (19%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

10.9%

20 terminated out of 183 trials

Success Rate

70.6%

-16.0% vs benchmark

Late-Stage Pipeline

11%

21 trials in Phase 3/4

Results Transparency

71%

34 of 48 completed with results

Key Signals

34 with results71% success20 terminated

Data Visualizations

Phase Distribution

166Total
Not Applicable (4)
Early P 1 (1)
P 1 (54)
P 2 (86)
P 3 (20)
P 4 (1)

Trial Status

Completed48
Recruiting47
Active Not Recruiting26
Terminated20
Not Yet Recruiting19
Unknown17

Trial Success Rate

70.6%

Benchmark: 86.5%

Based on 48 completed trials

Clinical Trials (183)

Showing 20 of 20 trials
NCT03604991Phase 2Suspended

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

NCT04615013Phase 1Recruiting

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

NCT05476796Phase 2Active Not Recruiting

Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer

NCT06131840Phase 1Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT06157892Phase 2Active Not Recruiting

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

NCT07043400Phase 3Recruiting

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT06243757Active Not Recruiting

A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers

NCT07090499Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

NCT06628310Phase 2Active Not Recruiting

A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

NCT07709767Phase 2Not Yet Recruiting

Conversion Therapy With Retlirafusp Alfa Plus Chemotherapy in Gastric or Gastroesophageal Junction Adenocarcinoma

NCT05111626Phase 3Terminated

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.

NCT06047379Phase 1Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

NCT04661150Phase 2Active Not Recruiting

A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction

NCT07701681Phase 2Not Yet Recruiting

Sacituzumab Tirumotecan (Sac-TMT/SKB264) Plus Tagitanlimab (KL-A167) in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma and Gastric/Gastroesophageal Junction Adenocarcinoma

NCT06324357Phase 1Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

NCT07689292Phase 2Not Yet Recruiting

Sac-TMT Combined With Fruquintinib as Second-Line Treatment in Patients With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

NCT07518147Phase 3Recruiting

A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment

NCT07689851Phase 2Recruiting

Chemoradiotherapy and SHR-1701 in Patients With Unresectable Gastric Cancer

NCT04375605Phase 3CompletedPrimary

Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ

NCT07621484Phase 2Not Yet Recruiting

HIPEC Priming Followed by Serplulimab Plus SOX/XELOX in Locally Advanced Gastric Cancer

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