Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

8.1%

3 terminated out of 37 trials

Success Rate

76.9%

-9.6% vs benchmark

Late-Stage Pipeline

8%

3 trials in Phase 3/4

Results Transparency

50%

5 of 10 completed with results

Key Signals

5 with results77% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (27)
P 4 (3)

Trial Status

Completed10
Unknown8
Recruiting6
Active Not Recruiting4
Terminated3
Not Yet Recruiting3

Trial Success Rate

76.9%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT03929913Not ApplicableCompletedPrimary

NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study

NCT05920824Recruiting

Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

NCT03142152Not ApplicableRecruitingPrimary

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

NCT03706833Not ApplicableActive Not Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

NCT03433274Not ApplicableActive Not Recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

NCT07131631Recruiting

Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance

NCT05991284Phase 4Active Not Recruiting

Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation

NCT05965258Recruiting

Phenotypic Classification of FMR With CMR

NCT06583876Not ApplicableRecruitingPrimary

Bio Refine for Functional Mitral Regurgitation - a Safety & Feasibility Study

NCT06823700Not ApplicableRecruitingPrimary

Safety and Effectiveness Study of SQ-Kyrin System for Functional Mitral Regurgitation in EU

NCT06814210Not ApplicableNot Yet Recruiting

CAP-TEER: CerebrAl Protection During Transcatheter Edge-to-edge Repair

NCT04666467Not ApplicableWithdrawnPrimary

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation ( EXPLORE FMR )

NCT03016975Not ApplicableTerminatedPrimary

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)

NCT05988450Not ApplicableActive Not RecruitingPrimary

Safety and Effectiveness Study of SQ-Kyrin TMVr System for Functional Mitral Regurgitation

NCT05931900Not ApplicableUnknownPrimary

The JensClip Transcatheter Valve Repair System for Treating Functional Mitral Regurgitation

NCT05865938Completed

PASCAL vs. MitralClip for Mitral Valve Transchatheter Edge-to-Edge Repair

NCT05848102Phase 4UnknownPrimary

Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Fibrosis (DEFORM)

NCT05774808Completed

Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitation

NCT04529928Not ApplicableTerminatedPrimary

An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation

NCT05677568Enrolling By InvitationPrimary

The CINCH-FMR Post-Market Registry: Percutaneous Repair in Functional Mitral Regurgitation

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Research Network

Activity Timeline