Key Insights

Highlights

Success Rate

66% trial completion

Published Results

80 trials with published results (24%)

Research Maturity

109 completed trials (32% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

16.9%

57 terminated out of 338 trials

Success Rate

65.7%

-20.8% vs benchmark

Late-Stage Pipeline

11%

37 trials in Phase 3/4

Results Transparency

73%

80 of 109 completed with results

Key Signals

80 with results66% success57 terminated

Data Visualizations

Phase Distribution

292Total
Not Applicable (14)
Early P 1 (5)
P 1 (118)
P 2 (118)
P 3 (36)
P 4 (1)

Trial Status

Completed109
Recruiting74
Terminated57
Unknown37
Active Not Recruiting34
Not Yet Recruiting15

Trial Success Rate

65.7%

Benchmark: 86.5%

Based on 109 completed trials

Clinical Trials (338)

Showing 20 of 20 trials
NCT06043323Phase 2RecruitingPrimary

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

NCT06112847Phase 2Active Not RecruitingPrimary

Lenalidomide and Epcoritamab for the Treatment of Previously Untreated Follicular Lymphoma

NCT04542824Phase 1Active Not Recruiting

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

NCT04663347Phase 1Active Not Recruiting

Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)

NCT07555470Phase 2Not Yet RecruitingPrimary

Mosunetuzumab and Zeprumetostat in Treating Patients With Follicular Lymphoma

NCT07282548WithdrawnPrimary

Study of Tazemetostat in Adults With Follicular Lymphoma Previously Treated With at Least Two Therapies

NCT04594642Phase 1Recruiting

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

NCT03190928RecruitingPrimary

Clonal Evolution in Follicular Lymphoma

NCT02315612Phase 1Completed

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

NCT04989621Phase 2RecruitingPrimary

Orelabrutinib Plus Rituximab Followed by Maintenance With Orelabrutinib for Relapsed and Refractory Follicular Lymphoma(RR FL)

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT04224493Phase 3Active Not Recruiting

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

NCT05294731Phase 1Recruiting

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

NCT07226843Phase 1Not Yet Recruiting

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

NCT04491370Phase 1Recruiting

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

NCT06544265Phase 1Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT01804686Phase 3Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT05994235Phase 2Active Not RecruitingPrimary

Tazemetostat and Mosunetuzumab in Untreated Follicular Lymphoma

NCT05618366Phase 1Terminated

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

NCT06971848Not ApplicableNot Yet Recruiting

Evaluation of Skin Tests in Biotherapy Allergies

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