Key Insights

Highlights

Success Rate

77% trial completion

Published Results

12 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

12.7%

7 terminated out of 55 trials

Success Rate

76.7%

-9.8% vs benchmark

Late-Stage Pipeline

11%

6 trials in Phase 3/4

Results Transparency

52%

12 of 23 completed with results

Key Signals

12 with results77% success

Data Visualizations

Phase Distribution

42Total
Not Applicable (9)
Early P 1 (1)
P 1 (9)
P 2 (17)
P 3 (3)
P 4 (3)

Trial Status

Completed23
Recruiting17
Terminated7
Unknown4
Active Not Recruiting2
Withdrawn1

Trial Success Rate

76.7%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (55)

Showing 20 of 20 trials
NCT04571658Not ApplicableRecruiting

NEPTUNE Match Study

NCT06664814Phase 2RecruitingPrimary

An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis

NCT06500702Phase 2RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT05650619RecruitingPrimary

Recurrence Post-transplant Observational Study in Focal Segmental Glomerulosclerosis and Minimal Change Disease

NCT07220083Phase 3RecruitingPrimary

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

NCT00001393CompletedPrimary

Genetic Markers for Focal Segmental Glomerulosclerosis

NCT07268638Phase 2RecruitingPrimary

A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)

NCT03493685Phase 3CompletedPrimary

Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)

NCT05583942Not ApplicableRecruiting

A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS)

NCT05588063Not ApplicableRecruiting

taVNS for FRNS in Children

NCT07219121Phase 4Recruiting

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

NCT06090227Phase 1RecruitingPrimary

AMPK-activation by Metformin in FSGS: AMP-FSGS

NCT05003986Phase 2RecruitingPrimary

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

NCT05267262Phase 2Completed

Study to Evaluate R3R01 in Patients With Alport Syndrome and Patients With Focal Segmental Glomerulosclerosis

NCT03763643Early Phase 1CompletedPrimary

PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

NCT04573920Phase 2Active Not Recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases

NCT03366337Phase 2Completed

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX

NCT01613118Phase 2CompletedPrimary

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis

NCT02235857Not ApplicableRecruitingPrimary

Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

NCT03703908Phase 2TerminatedPrimary

A Study of CCX140-B in Subjects With Primary FSGS and Nephrotic Syndrome

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