Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

10.0%

4 terminated out of 40 trials

Success Rate

87.5%

+1.0% vs benchmark

Late-Stage Pipeline

8%

3 trials in Phase 3/4

Results Transparency

32%

9 of 28 completed with results

Key Signals

9 with results88% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (4)
Early P 1 (1)
P 1 (14)
P 2 (15)
P 3 (3)

Trial Status

Completed28
Terminated4
Unknown2
Withdrawn2
Recruiting2
Not Yet Recruiting1

Trial Success Rate

87.5%

Benchmark: 86.5%

Based on 28 completed trials

Clinical Trials (40)

Showing 20 of 20 trials
NCT03442465Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

NCT07048249Early Phase 1RecruitingPrimary

Single Arm Romiplostim to Prevent CIT

NCT02162732Not ApplicableCompleted

Molecular-Guided Therapy for Childhood Cancer

NCT04671693Not ApplicableActive Not Recruiting

A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.

NCT07092306Phase 2Not Yet RecruitingPrimary

A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's Sarcoma

NCT01336803Phase 2Completed

Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI

NCT02736565Phase 1CompletedPrimary

Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma

NCT02890758Phase 1Completed

Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803

NCT02511132Phase 2CompletedPrimary

A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma

NCT02063022Phase 3CompletedPrimary

Efficacy of Dose Intensification in Patients With Non-metastatic Ewing Sarcoma

NCT01061840Phase 1CompletedPrimary

Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer

NCT01222767Phase 2CompletedPrimary

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

NCT00001686CompletedPrimary

Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare Diseases

NCT01331135Phase 1CompletedPrimary

Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors

NCT02390843Phase 1Completed

Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors

NCT00038142Phase 2TerminatedPrimary

Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) in High Risk Ewing's Sarcoma Patients

NCT01962103Phase 1Completed

Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

NCT00428272Phase 1TerminatedPrimary

HGS-ETR2 to Treat Children With Solid Tumors

NCT00001564Phase 2CompletedPrimary

A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas

NCT00004853Phase 1CompletedPrimary

Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapy

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Research Network

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