Key Insights

Highlights

Success Rate

68% trial completion

Published Results

16 trials with published results (15%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.2%

12 terminated out of 107 trials

Success Rate

68.4%

-18.1% vs benchmark

Late-Stage Pipeline

2%

2 trials in Phase 3/4

Results Transparency

62%

16 of 26 completed with results

Key Signals

16 with results68% success12 terminated

Data Visualizations

Phase Distribution

91Total
Not Applicable (12)
Early P 1 (1)
P 1 (54)
P 2 (22)
P 3 (2)

Trial Status

Recruiting37
Completed26
Unknown13
Active Not Recruiting12
Terminated12
Withdrawn4

Trial Success Rate

68.4%

Benchmark: 86.5%

Based on 26 completed trials

Clinical Trials (107)

Showing 20 of 20 trials
NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT07321912Phase 2Recruiting

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

NCT07297979Phase 1RecruitingPrimary

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT07188532Not ApplicableRecruitingPrimary

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial

NCT07620431Not Yet RecruitingPrimary

Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma

NCT07197554Phase 1Recruiting

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

NCT03715933Phase 1RecruitingPrimary

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

NCT07172958Phase 1Recruiting

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT04337177Phase 1Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT06068075Not ApplicableActive Not RecruitingPrimary

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

NCT06094101Phase 1RecruitingPrimary

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)

NCT04483778Phase 1Active Not Recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT00840047Phase 2Active Not Recruiting

Methionine PET/CT Studies In Patients With Cancer

NCT06926283Phase 1Recruiting

A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors

NCT07514819Not ApplicableNot Yet Recruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT06796543Not ApplicableRecruiting

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

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