Key Insights

Highlights

Success Rate

68% trial completion

Published Results

16 trials with published results (14%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.8%

12 terminated out of 111 trials

Success Rate

68.4%

-18.2% vs benchmark

Late-Stage Pipeline

2%

2 trials in Phase 3/4

Results Transparency

62%

16 of 26 completed with results

Key Signals

16 with results68% success12 terminated

Data Visualizations

Phase Distribution

94Total
Not Applicable (12)
Early P 1 (1)
P 1 (55)
P 2 (24)
P 3 (2)

Trial Status

Recruiting40
Completed26
Terminated12
Active Not Recruiting12
Unknown11
Not Yet Recruiting6

Trial Success Rate

68.4%

Benchmark: 86.6%

Based on 26 completed trials

Clinical Trials (111)

Showing 20 of 20 trials
NCT03478462Phase 1Active Not Recruiting

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

NCT03373097Phase 1Active Not Recruiting

Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors

NCT07297979Phase 1RecruitingPrimary

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

NCT06926283Phase 1Recruiting

A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT07695311Phase 1Not Yet RecruitingPrimary

EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

NCT03715933Phase 1RecruitingPrimary

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT06156410Phase 1RecruitingPrimary

Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

NCT06541262Phase 1Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT05918640Phase 1RecruitingPrimary

Lurbinectedin in FET-Fused Tumors

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT03356782Phase 1Not Yet Recruiting

Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas

NCT04433221Phase 1Not Yet Recruiting

Combination Immunotherapy Targeting Sarcomas

NCT07781891Phase 2Not Yet RecruitingPrimary

RAPID: Phase 2 Platform Trial Of Promising Drugs For AYA Patients With R/R Ewing Sarcoma & DSRCT

NCT07514819Not ApplicableRecruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT05968768Phase 2RecruitingPrimary

To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)

NCT07172958Phase 1Recruiting

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT04337177Phase 1Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

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