Key Insights

Highlights

Success Rate

68% trial completion

Published Results

16 trials with published results (15%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.9%

12 terminated out of 110 trials

Success Rate

68.4%

-18.1% vs benchmark

Late-Stage Pipeline

2%

2 trials in Phase 3/4

Results Transparency

62%

16 of 26 completed with results

Key Signals

16 with results68% success12 terminated

Data Visualizations

Phase Distribution

93Total
Not Applicable (12)
Early P 1 (1)
P 1 (55)
P 2 (23)
P 3 (2)

Trial Status

Recruiting41
Completed26
Terminated12
Active Not Recruiting12
Unknown11
Withdrawn4

Trial Success Rate

68.4%

Benchmark: 86.5%

Based on 26 completed trials

Clinical Trials (110)

Showing 20 of 20 trials
NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT04337177Phase 1Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT06395103Phase 1Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT07725783RecruitingPrimary

Prospective Evaluation of Dynamic Serum ProGRP for Treatment Response Monitoring in Ewing Sarcoma

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT07695311Phase 1Not Yet RecruitingPrimary

EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

NCT07297979Phase 1RecruitingPrimary

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

NCT06796543Not ApplicableRecruiting

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT07321912Phase 2Recruiting

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

NCT06926283Phase 1Recruiting

A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors

NCT06541262Phase 1Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT07514819Not ApplicableNot Yet Recruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT06625190Phase 1Recruiting

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT03356782Phase 1Recruiting

Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas

NCT04433221Phase 1Recruiting

Combination Immunotherapy Targeting Sarcomas

NCT06571734Phase 2Recruiting

XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma

NCT00840047Phase 2Active Not Recruiting

Methionine PET/CT Studies In Patients With Cancer

NCT07188532Not ApplicableRecruitingPrimary

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial

NCT07620431Not Yet RecruitingPrimary

Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma

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