Estrogen Receptor Positive Breast Cancer
19
0
5
6
Key Insights
Highlights
Success Rate
55% trial completion
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 65/100
26.3%
5 terminated out of 19 trials
54.5%
-32.0% vs benchmark
11%
2 trials in Phase 3/4
67%
4 of 6 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 6 completed trials
Clinical Trials (19)
Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer
[18F]FES PET/CT in Endocrine Refractory Breast Cancer
Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer
REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy
Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer
Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer
FDG PET/CT in Breast Cancer Bone Mets
Evaluation of a Novel Technique for the Discovery of New, Tumor-specific Targets for the Deployment of Innovative Immunotherapeutics Against Cancer.
A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers
A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer
[18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial
Early Changes in Metabolic Health in Breast Cancer Patients Initiating Endocrine Therapy
A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older
Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor
Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer
TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer
A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Hydroxychloroquine in Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Hormonal Therapy
A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)