Key Insights

Highlights

Success Rate

64% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

21.1%

4 terminated out of 19 trials

Success Rate

63.6%

-22.9% vs benchmark

Late-Stage Pipeline

11%

2 trials in Phase 3/4

Results Transparency

57%

4 of 7 completed with results

Key Signals

4 with results64% success

Data Visualizations

Phase Distribution

16Total
Not Applicable (2)
Early P 1 (1)
P 1 (4)
P 2 (7)
P 3 (2)

Trial Status

Completed7
Active Not Recruiting5
Terminated4
Unknown1
Not Yet Recruiting1
Enrolling By Invitation1

Trial Success Rate

63.6%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT02947685Phase 3Active Not Recruiting

Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

NCT00066690Phase 3CompletedPrimary

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

NCT01984138Phase 2Active Not RecruitingPrimary

REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

NCT02668666Phase 2Completed

Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer

NCT01992952Phase 1Active Not RecruitingPrimary

Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer

NCT01996046Active Not RecruitingPrimary

FDG PET/CT in Breast Cancer Bone Mets

NCT06629233Not ApplicableEnrolling By InvitationPrimary

Evaluation of a Novel Technique for the Discovery of New, Tumor-specific Targets for the Deployment of Innovative Immunotherapeutics Against Cancer.

NCT02409316Phase 2CompletedPrimary

[18F]FES PET/CT in Endocrine Refractory Breast Cancer

NCT02238808Phase 2Active Not RecruitingPrimary

A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers

NCT02216786Phase 2CompletedPrimary

A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer

NCT04727632Early Phase 1TerminatedPrimary

[18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial

NCT06623903Not Yet Recruiting

Early Changes in Metabolic Health in Breast Cancer Patients Initiating Endocrine Therapy

NCT02823262Not ApplicableTerminated

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older

NCT01765049Unknown

Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor

NCT02820961Phase 1Completed

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

NCT02988986Phase 2CompletedPrimary

TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer

NCT01219699Phase 1Completed

A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene

NCT02414776Phase 1TerminatedPrimary

Hydroxychloroquine in Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Hormonal Therapy

NCT02000375Phase 2Terminated

A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)

Showing all 19 trials

Research Network

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