Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

3.0%

1 terminated out of 33 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

0%

0 of 6 completed with results

Key Signals

86% success

Data Visualizations

Phase Distribution

25Total
Not Applicable (22)
P 2 (2)
P 3 (1)

Trial Status

Unknown15
Recruiting8
Completed6
Not Yet Recruiting2
Withdrawn1
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT00260585Recruiting

Esophageal Cancer Risk Registry

NCT06721520Phase 2Recruiting

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

NCT07425977Phase 3Not Yet RecruitingPrimary

Transverse vs Longitudinal Mucosal Incision During POEM

NCT05899842Not ApplicableRecruitingPrimary

Routine Versus Symptomatic Protein Pump Inhibitor Therapy for Prevention of Gastroesophageal Reflux After Per Oral Endoscopic Myotomy for Esophageal Achalasia

NCT04578769Not ApplicableRecruitingPrimary

Assessment of Different Modified POEM for Achalasia

NCT06405412RecruitingPrimary

Effects of Malnutrition on Respiratory and Renal Functions in Patients Undergoing Peroral Endoscopic Myotomy (POEM)

NCT06230536RecruitingPrimary

MARIMPACH : Contribution of High-resolution Manometry With Impedancemetry for the Evaluation of Esophageal Clearance in Achalasia

NCT02606578TerminatedPrimary

Achalasia Patient Reported Outcomes

NCT06264466Not ApplicableRecruitingPrimary

Safety and Efficacy of a Novel Flexible Bipolar in POEM

NCT04112693Not ApplicableCompletedPrimary

Assessment of the Neuro-glio-epithelial Unit (NGEU) in Biopsies Taken During Peroral Endoscopic Myotomy (POEM) for Achalasia: a Feasibility and Safety Study.

NCT06027190Not ApplicableNot Yet RecruitingPrimary

Randomized Controlled Study of Optical 3D Navigated Repetitive Transcranial Magnetic Stimulation for Achalasia.

NCT05113173UnknownPrimary

Study on the Relationship Between Pathological Features of Achalasia and Prognosis of Per-oral Endoscopic Myotomy

NCT05602272UnknownPrimary

Respiratory and Hemodynamic Implications of Endoscopic Myotomy of the Esophagus and Stomach

NCT05010889UnknownPrimary

Quality of Life After POEM for Achalasia

NCT03962179Not ApplicableUnknown

Feasibility and Efficacy of a Combination of a SEMS and Vacuum Wound Treatment (VACStent)

NCT03702647Not ApplicableCompleted

Ropivacaine For Post-POEM Pain Control

NCT02999451Not ApplicableCompletedPrimary

Snare-assisted POEM for Treatment of Esophageal Achalasia

NCT03944863Completed

Impact of Antibiotic Prophylaxis in Per-oral Endoscopic Myotomy for Esophageal Motor Disorders

NCT03733756Not ApplicableUnknownPrimary

to Explore the Influence of Longitudinal Muscle on the Prognosis of Achalasia Patients After Peroral Endoscopic Myotomy (POEM)

NCT03404739Phase 2UnknownPrimary

Single- Versus Multiple-dose Antimicrobial Prophylaxis for The Prevention of Infectious Complications Associated With Peroral Endoscopic Myotomy(POEM) for Achalasia

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