Key Insights

Highlights

Success Rate

68% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

16.7%

8 terminated out of 48 trials

Success Rate

68.0%

-18.5% vs benchmark

Late-Stage Pipeline

21%

10 trials in Phase 3/4

Results Transparency

29%

5 of 17 completed with results

Key Signals

5 with results68% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (16)
P 1 (1)
P 2 (1)
P 4 (10)

Trial Status

Completed17
Unknown9
Recruiting9
Terminated8
Not Yet Recruiting2
Active Not Recruiting2

Trial Success Rate

68.0%

Benchmark: 86.5%

Based on 17 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT05156437Phase 4TerminatedPrimary

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)

NCT05547607RecruitingPrimary

Clinical and Diagnostic Features of Endocarditis

NCT05378126Not ApplicableCompletedPrimary

Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis

NCT06489535Not ApplicableActive Not Recruiting

Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)

NCT05146180Not ApplicableRecruitingPrimary

Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis

NCT02026895Not ApplicableCompleted

Virulence of Staphylococcus Lugdunensis in Severe Infections

NCT06403839Recruiting

Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients

NCT06434012Recruiting

Barts Endocarditis Research Registry

NCT03718052Not ApplicableActive Not RecruitingPrimary

Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of Embolism

NCT05703022Not ApplicableCompletedPrimary

Early Exercise Training in Patients Following Heart Valve Surgery for Infective Endocarditis.

NCT05432427Not ApplicableCompletedPrimary

64Cu-DOTATATE PET-CT-skanning and Infective Endocarditis.

NCT03892174Not ApplicableRecruitingPrimary

Cytokine REmoval in CRitically Ill PAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE)

NCT06422221Phase 4Not Yet Recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

NCT06275100Not ApplicableRecruiting

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry

NCT06330766Recruiting

Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients

NCT05144399Phase 4RecruitingPrimary

Accelerated Treatment of Endocarditis

NCT03411499Not ApplicableTerminatedPrimary

Stroke-free Survival Comparison Between Early Surgery and Conventional Therapy in Left Infective Endocarditis

NCT06107309UnknownPrimary

Suppressive Antibiotic Therapy for Endocarditis

NCT01431326Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT05139589RecruitingPrimary

The ENDOCARDITIS AUMC Data Collection

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Research Network

Activity Timeline